The use of zebrafish (Danio rerio) has arisen as a promising biological platform for toxicity
testing of pesticides such as herbicides, insecticides, and fungicides. Therefore, it is relevant …

Although it is widely accepted that better food habits do play important role in cancer
prevention and treatment, how dietary agents mediate their effects remains poorly …

Aldehyde dehydrogenase is a polymorphic enzyme, which responsible for the oxidation of
aldehydes. It has been shown that ALDH1A3 is expressed in human glioblastomas and that …

Deguelin is a rotenoid of the flavonoid family, which can be extracted from Lonchocarpus,
Derris, or Tephrosia. It possesses the inhibition of cancer cell proliferation by inducing …

Background: Metastasis is often derived from increased invasion and migration of tumor
cells, and is the most frequent cause of cancer-associated death. Either the prophylactic or …

Deguelin is a rotenoid compound that exists in abundant quantities in the bark, roots, and
leaves of the Leguminosae family of plants. An analysis of evidence from both in vitro and in …

Background/Aims: TGF-β1 is beneficial during early liver disease but is tumor-progressive
during late stages especially for hepatocellular carcinoma (HCC). Thus, exploring the …

Angiogenesis plays a crucial role in the development of human hepatocellular carcinoma
(HCC). In the present study, we found a natural compound, deguelin, has a profound anti …

Deguelin, a plant retinoid has emerged to be a promising therapeutic agent in the treatment
of different cancers. Recent studies demonstrate that deguelin has potential as an …

As a result of limited classes of anthelmintics and an over‐reliance on chemical control,
there is a great need to discover new compounds to combat drug resistance in parasitic …