Tissue factor (TF) is the high-affinity receptor and cofactor for factor (F) VII/VIIa. The TF-FVIIa
complex is the primary initiator of blood coagulation and plays an essential role in …

Severe hemorrhage has posed a serious threat to the health and even life of civilian and
military populations and brought serious economic losses. Consequently, it is imperative to …

Atrial fibrillation is the most common sustained cardiac arrhythmia, which is associated with
a high risk of stroke and thromboembolism. Increasing evidence suggests that the …

Microparticles (MPs) derived from platelets, monocytes, endothelial cells, red blood cells,
and granulocytes may be detected in low concentrations in normal plasma and at increased …

Using a laser-induced endothelial injury model, we examined thrombus formation in the
microcirculation of wild-type and genetically altered mice by real-time in vivo microscopy to …

Glioblastoma (GBM) is a highly malignant, rapidly progressive astrocytoma that is
distinguished pathologically from lower grade tumors by necrosis and microvascular …

We have used confocal and widefield microscopy to image thrombus formation in real time
in the microcirculation of a living mouse. This system provides high-speed, near …

Background Intraportal transplantation of pancreatic islets offers improved glycaemic control
and insulin independence in type 1 diabetes mellitus, but intraportal thrombosis remains a …

It has been widely accepted that microparticles expose phosphatidylserine which in turn
binds annexin V. It was the objective of this study to compare the antigenic characteristics …

The protein C system provides important control of blood coagulation by regulating the
activities of factor VIIIa (FVIIIa) and factor Va (FVa), cofactors in the activation of factor X and …