A review on the traditional uses, phytochemistry, and pharmacological activities of clove basil (Ocimum gratissimum L.)

OC Ugbogu, O Emmanuel, GO Agi, C Ibe, CN Ekweogu… - Heliyon, 2021 - cell.com
In traditional medicine, Ocimum gratissimum (clove basil) is used in the treatment of various
diseases such as diabetes, cancer, inflammation, anaemia, diarrhoea, pains, and fungal and …

Medicinal plants as a potential source of Phosphodiesterase-5 inhibitors: A review

AA Ganapathy, VMH Priya, A Kumaran - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance The prevalence and distress caused by erectile
dysfunction (ED) to both male and female partners are increasing at a steady rate. ED has …

[HTML][HTML] Promising role of medicinal plants in the regulation and management of male erectile dysfunction

NP Masuku, JO Unuofin, SL Lebelo - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Male erectile dysfunction (ED) refers to incompetency to reaching and retaining adequate
penile tumescence for sexual intercourse. Over 152 million men globally suffer from ED and …

Botanical medicine and natural products used for erectile dysfunction

VJE Sin, GS Anand, HL Koh - Sexual Medicine Reviews, 2021 - academic.oup.com
Introduction Erectile dysfunction is the persistent or recurrent inability to achieve or maintain
an erection sufficient for intercourse. Despite various treatment options, not all patients …

[HTML][HTML] Network pharmacology based anti-diabetic attributes of bioactive compounds from Ocimum gratissimum L. through computational approach

RY Halayal, ZK Bagewadi, RB Maliger… - Saudi Journal of …, 2023 - Elsevier
The present research was framed to determine the key compounds present in the plant
Ocimum gratissimum L. targeting protein molecules of Diabetes Mellitus (DM) by employing …

Ocimum tenuiflorum mitigates iron‐induced testicular toxicity via modulation of redox imbalance, cholinergic and purinergic dysfunctions, and glucose metabolizing …

KA Olofinsan, VF Salau, OL Erukainure, MS Islam - Andrologia, 2021 - Wiley Online Library
Oxidative stress is a primary culprit in the pathophysiology of infertility conditions in males.
This study investigated the effects of Ocimum tenuiflorum on redox imbalance, cholinergic …

[HTML][HTML] Anti-apoptotic and antioxidant mechanisms may underlie the abrogative potential of Ocimum gratissimum Linn. Leaf extract and fractions against trastuzumab …

OE Olorundare, AA Adeneye, AO Akinsola, AM Ajayi… - Toxicology Reports, 2024 - Elsevier
Clinical use of trastuzumab (TZM), has been widely associated with increased incidence of
cardiotoxicity. Ocimum gratissimum Linn. is a household medicinal plant popularly used for …

Exploring the potentials of some compounds from Garcinia kola seeds towards identification of novel PDE‐5 inhibitors in erectile dysfunction therapy

OA Ojo, AB Ojo, RF Maimako, D Rotimi… - Andrologia, 2021 - Wiley Online Library
Erectile dysfunction (ED) is one of the main challenges occurring among men worldwide,
and is characterised by trouble getting or kee** steady erection during sexual intercourse …

Inhibitory potentials of phytocompounds from Ocimum gratissimum against anti-apoptotic BCL-2 proteins associated with cancer: an integrated computational study

G A. Gyebi, O M. Ogunyemi, I M. Ibrahim… - Egyptian Journal of …, 2022 - Taylor & Francis
The anti-apoptotic Bcl-2 family is intrinsically involved in regulating apoptosis. Over
expression of these proteins is associated with cancer. Thus, inhibitors of these proteins will …

Diet, herbs and erectile function: A good friendship!

AA Olabiyi, K Ajayi - Andrologia, 2022 - Wiley Online Library
Plants and plant materials have been used for thousands of years to treat and control
erectile dysfunction in men. This practice has spanned many cultures and traditions around …