Context Focal therapy is a promising, minimally invasive strategy to selectively treat
localized prostate cancer. A previous systematic review indicated that there is growing …

Introduction Whilst whole‐gland radical treatment is highly effective for prostate cancer
control, it has significant impact on quality of life and is unnecessary 'over‐treatment'in many …

Radical treatment of localised prostate cancer is recognised to be an unnecessary
intervention or overtreatment in many men. Consequently, there has been a rapid uptake in …

Importance Focal therapy of prostate cancer must balance the oncologic outcome and
functional outcome. High-frequency irreversible electroporation (H-FIRE) can destroy cancer …

Background Focal irreversible electroporation (IRE) can be used to treat men with localised
prostate cancer (PCa) with reduced impact on quality of life (QoL). Objective To assess …

Objectives To determine the safety, quality of life (QoL) and short‐term oncological
outcomes of primary focal irreversible electroporation (IRE) for the treatment of localized …

Background Irreversible electroporation (IRE) is a nonthermal ablative method based on the
formation of nanoscale defects in cell membranes leading to cell death. Clinical experience …

Objective: This study sought to investigate a novel strategy using temperature-controlled
delivery of nanosecond pulsed electric fields as an alternative to the 50-100 microsecond …

Background The Purkinje network appears to play a pivotal role in the triggering as well as
maintenance of ventricular fibrillation. Irreversible electroporation (IRE) using direct current …

Introduction and objective To assess the safety, oncological and quality-of-life (QoL)
outcomes of focal ablation of apical prostate cancer (PCa) lesions with irreversible …