A review of cytokine-based pathophysiology of Long COVID symptoms

RN Low, RJ Low, A Akrami - Frontiers in medicine, 2023 - frontiersin.org
The Long COVID/Post Acute Sequelae of COVID-19 (PASC) group includes patients with
initial mild-to-moderate symptoms during the acute phase of the illness, in whom recovery is …

Mucosal immune response in biology, disease prevention and treatment

X Zhou, Y Wu, Z Zhu, C Lu, C Zhang, L Zeng… - … and Targeted Therapy, 2025 - nature.com
The mucosal immune system, as the most extensive peripheral immune network, serves as
the frontline defense against a myriad of microbial and dietary antigens. It is crucial in …

SARS-CoV-2 infects cells lining the blood-retinal barrier and induces a hyperinflammatory immune response in the retina via systemic exposure

M Monu, F Ahmad, RM Olson, V Balendiran… - Plos …, 2024 - journals.plos.org
SARS-CoV-2 has been shown to cause wide-ranging ocular abnormalities and vision
impairment in COVID-19 patients. However, there is limited understanding of SARS-CoV-2 …

Direct and indirect impact of SARS-CoV-2 on the brain

JPS Peron - Human Genetics, 2023 - Springer
Although COVID-19 is mostly a pulmonary disease, it is now well accepted that it can cause
a much broader spectrum of signs and symptoms and affect many other organs and tissue …

Neurological disorders after severe pneumonia are associated with translocation of endogenous bacteria from the lung to the brain

Q Ma, C Yao, Y Wu, H Wang, Q Fan, Q Yang, J Xu… - Science …, 2023 - science.org
Neurological disorders are a common feature in patients who recover from severe acute
pneumonia. However, the underlying mechanisms remain poorly understood. Here, we …

Characterizing neuroinvasion and neuropathology of SARS-CoV-2 by using AC70 human ACE2 transgenic mice

JC Hsu, P Saenkham-Huntsinger, P Huang… - Frontiers in …, 2024 - frontiersin.org
COVID-19 presents with a plethora of neurological signs and symptoms despite being
characterized as a respiratory disease, including seizures, anxiety, depression, amnesia …

[HTML][HTML] Exploring the role of the ocular surface in the lung-eye axis: Insights into respiratory disease pathogenesis

VSRR Allam, VK Patel, G De Rubis, KR Paudel… - Life Sciences, 2024 - Elsevier
Chronic respiratory diseases (CRDs) represent a significant proportion of global health
burden, with a wide spectrum of varying, heterogenic conditions largely affecting the …

Ocular A-to-I RNA editing signatures associated with SARS-CoV-2 infection

YY **, YP Liang, WH Huang, L Guo, LL Cheng… - BMC genomics, 2024 - Springer
Ophthalmic manifestations have recently been observed in acute and post-acute
complications of COVID-19 caused by SARS-CoV-2 infection. Our precious study has shown …

A single-dose intranasal live-attenuated codon deoptimized vaccine provides broad protection against SARS-CoV-2 and its variants

X Liu, WH Ng, E Zusinaite, J Freitas, A Taylor… - Nature …, 2024 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) continues its
significant health and economic impact globally. Despite the success of spike-protein …

Study on brain damage patterns of COVID-19 patients based on EEG signals

Y Yao, Y Liu, Y Chang, Z Geng, X Liu, S Ma… - Frontiers in Human …, 2023 - frontiersin.org
Objective The coronavirus disease 2019 (COVID-19) is an acute respiratory infectious
disease caused by the SARA-CoV-2, characterized by high infectivity and incidence. Clinical …