Molecular pathogenesis of Merkel cell carcinoma
JA DeCaprio - Annual Review of Pathology: Mechanisms of …, 2021 - annualreviews.org
Merkel cell carcinoma (MCC) is an aggressive neuroendocrine carcinoma of the skin with
two distinct etiologies. Clonal integration of Merkel cell polyomavirus DNA into the tumor …
two distinct etiologies. Clonal integration of Merkel cell polyomavirus DNA into the tumor …
BK polyomavirus: clinical aspects, immune regulation, and emerging therapies
SUMMARY BK polyomavirus (BKV) causes frequent infections during childhood and
establishes persistent infections within renal tubular cells and the uroepithelium, with …
establishes persistent infections within renal tubular cells and the uroepithelium, with …
Biology, evolution, and medical importance of polyomaviruses: An update
U Moens, A Krumbholz, B Ehlers, R Zell… - Infection, Genetics and …, 2017 - Elsevier
The family Polyomaviridae encompasses non-enveloped viruses with a circular dsDNA
genome that is typically approximately 5000 bp in length. Originally isolated from mammals …
genome that is typically approximately 5000 bp in length. Originally isolated from mammals …
Need for speed: examining protein behavior during CryoEM grid preparation at different timescales
A host of new technologies are under development to improve the quality and reproducibility
of cryoelectron microscopy (cryoEM) grid preparation. Here we have systematically …
of cryoelectron microscopy (cryoEM) grid preparation. Here we have systematically …
Merkel cell polyomavirus and Merkel cell carcinoma
JA DeCaprio - … Transactions of the Royal Society B …, 2017 - royalsocietypublishing.org
Merkel cell polyomavirus (MCPyV) causes the highly aggressive and relatively rare skin
cancer known as Merkel cell carcinoma (MCC). MCPyV also causes a lifelong yet relatively …
cancer known as Merkel cell carcinoma (MCC). MCPyV also causes a lifelong yet relatively …
Biology of the BKPyV: an update
F Helle, E Brochot, L Handala, E Martin, S Castelain… - Viruses, 2017 - mdpi.com
The BK virus (BKPyV) is a member of the Polyomaviridae family first isolated in 1971. BKPyV
causes frequent infections during childhood and establishes persistent infections with …
causes frequent infections during childhood and establishes persistent infections with …
BK virus: current understanding of pathogenicity and clinical disease in transplantation
S Chong, M Antoni, A Macdonald… - Reviews in Medical …, 2019 - Wiley Online Library
BK polyomavirus (BKV) is an important cause of graft loss in renal transplant recipients that
continues to pose a significant challenge to clinicians due to its frequently unpredictable …
continues to pose a significant challenge to clinicians due to its frequently unpredictable …
BK polyomavirus—biology, genomic variation and diagnosis
J Furmaga, M Kowalczyk, T Zapolski, O Furmaga… - Viruses, 2021 - mdpi.com
The BK polyomavirus (BKPyV), a representative of the family Polyomaviridae, is widespread
in the human population. While the virus does not cause significant clinical symptoms in …
in the human population. While the virus does not cause significant clinical symptoms in …
Pathogenicity of avian polyomaviruses and prospect of vaccine development
CW Wang, YL Chen, SJT Mao, TC Lin, CW Wu… - Viruses, 2022 - mdpi.com
Polyomaviruses are nonenveloped icosahedral viruses with a double-stranded circular DNA
containing approximately 5000 bp and 5–6 open reading frames. In contrast to mammalian …
containing approximately 5000 bp and 5–6 open reading frames. In contrast to mammalian …
Human memory B cells harbor diverse cross-neutralizing antibodies against BK and JC polyomaviruses
JM Lindner, V Cornacchione, A Sathe, C Be, H Srinivas… - Immunity, 2019 - cell.com
Human polyomaviruses cause a common childhood infection worldwide and typically elicit a
neutralizing antibody and cellular immune response, while establishing a dormant infection …
neutralizing antibody and cellular immune response, while establishing a dormant infection …