High throughput screening of mutagenized populations

MJT Van Eijk, AJ van Tunen - US Patent 9,376,719, 2016 - Google Patents
Efficient methods are disclosed for the high throughput iden tification of mutations in genes
in members of mutagenized populations. The methods comprise DNA isolation, pooling …

ABL mutations in late chronic phase chronic myeloid leukemia patients with up-front cytogenetic resistance to imatinib are associated with a greater likelihood of …

S Soverini, G Martinelli, G Rosti, S Bassi… - Journal of clinical …, 2005 - ascopubs.org
Purpose Point mutations within the ABL kinase domain of the BCR-ABL gene have been
associated with clinical resistance to imatinib mesylate in chronic myeloid leukemia (CML) …

High throughput screening of mutagenized populations

MJT Van Eijk, AJ Van Tunen - 2007 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
37709618&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

A gold nanorods-based fluorescent biosensor for the detection of hepatitis B virus DNA based on fluorescence resonance energy transfer

X Lu, X Dong, K Zhang, X Han, X Fang, Y Zhang - Analyst, 2013 - pubs.rsc.org
In this study, we designed a fluorescence resonance energy transfer system containing gold
nanorods (AuNRs) and fluorescein (FAM) for the detection of hepatitis B virus DNA …

Single nucleotide polymorphism (SNP) discovery in mammals: a targeted‐gene approach

N Aitken, S Smith, C Schwarz, PA Morin - Molecular ecology, 2004 - Wiley Online Library
Single nucleotide polymorphisms (SNPs) have rarely been exploited in nonhuman and
nonmodel organism genetic studies. This is due partly to difficulties in finding SNPs in …

Snip** polymorphisms from large EST collections in barley (Hordeum vulgare L.)

R Kota, S Rudd, A Facius, G Kolesov, T Thiel… - Molecular Genetics and …, 2003 - Springer
The public EST (expressed sequence tag) databases represent an enormous but
heterogeneous repository of sequences, including many from a broad selection of plant …

Multiplex electrochemiluminescence DNA sensor for determination of hepatitis B virus and hepatitis C virus based on multicolor quantum dots and Au nanoparticles

L Liu, X Wang, Q Ma, Z Lin, S Chen, Y Li, L Lu, H Qu… - Analytica chimica …, 2016 - Elsevier
In this work, a novel multiplex electrochemiluminescence (ECL) DNA sensor has been
developed for determination of hepatitis B virus (HBV) and hepatitis C virus (HCV) based on …