Optogenetics is widely used to interrogate the neural circuits underlying disease and has
most recently been harnessed for therapeutic applications. The optogenetic toolkit consists …

Stroke induces a plastic state in the brain. This period of enhanced plasticity leads to the
sprouting of new axons, the formation of new synapses and the remap** of sensory-motor …

We tested a newly described molecular memory system, CCR5 signaling, for its role in
recovery after stroke and traumatic brain injury (TBI). CCR5 is uniquely expressed in cortical …

Background and Purpose: Neuronal pyroptosis is a type of regulated cell death triggered by
proinflammatory signals. CCR5 (CC chemokine receptor 5)-mediated inflammation is …

Background. Physical exercise (PE) has been associated with increase neuroplasticity,
neurotrophic factors, and improvements in brain function. Objective. To evaluate the effects …

cAMP responsive element-binding protein (CREB) is one of the most intensively studied
phosphorylation-dependent transcription factors that provide evolutionarily conserved …

Due to the widely usage in livestock, aquaculture and clinics, antibiotic residues are existed
in aqueous environments and their potential toxicity to aquatic organisms is concerning …

This study assesses the neuroprotective potential of CPP-P1, a conjugate of an anti-
apoptotic peptain-1 (P1) and a cell-penetrating peptide (CPP) in in vitro, in vivo, and ex vivo …

Stroke is a leading cause of death and disability in developed countries. N-methyl-D-
aspartate glutamate receptors (NMDARs) have important roles in stroke pathology and …

The disruption of the blood–brain barrier (BBB) plays a critical role in the pathology of
ischemic stroke. p75 neurotrophin receptor (p75NTR) contributes to the disruption of the …