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Immunology of leprosy
Leprosy is a disease caused by Mycobacterium leprae (ML) with diverse clinical
manifestations, which are strongly correlated with the host's immune response. Skin lesions …
manifestations, which are strongly correlated with the host's immune response. Skin lesions …
New insights into the pathogenesis of leprosy: contribution of subversion of host cell metabolism to bacterial persistence, disease progression, and transmission
Chronic infection by the obligate intracellular pathogen Mycobacterium leprae may lead to
the development of leprosy. Of note, in the lepromatous clinical form of the disease, failure of …
the development of leprosy. Of note, in the lepromatous clinical form of the disease, failure of …
Differential expression of programmed death 1 (PD-1) on various immune cells and its role in human leprosy
Leprosy is a chronic bacterial disease caused by Mycobacterium leprae. Leprosy patients
have been found to have defects in T cells activation, which is critical to the clearance of the …
have been found to have defects in T cells activation, which is critical to the clearance of the …
An update on leprosy immunopathogenesis: systematic review
Introduction Leprosy is a chronic infectious condition and the main cause of neuropathy that
occurs brought on by M. leprae. It is known that the biological characteristics of the human …
occurs brought on by M. leprae. It is known that the biological characteristics of the human …
[HTML][HTML] Reduced vitamin D receptor (VDR) and cathelicidin antimicrobial peptide (CAMP) gene expression contribute to the maintenance of inflammatory immune …
ALG de Oliveira, AT Chaves, MS Cardoso… - Microbes and …, 2022 - Elsevier
Leprosy is an infectious disease influenced by genetic, immunological, and environmental
factors. Reduced gene expressions may be associated with the immunological response …
factors. Reduced gene expressions may be associated with the immunological response …
Immunological biomarkers of subclinical infection in household contacts of leprosy patients
EA Queiroz, NI Medeiros, RT Mattos, APM Carvalho… - Immunobiology, 2019 - Elsevier
Hansen's disease (or leprosy) still persists as a serious public health issue. Its diagnosis is
based primarily on the detection of clinical signs that are characteristic of the disease …
based primarily on the detection of clinical signs that are characteristic of the disease …
Th17 cells and cytokines in leprosy: understanding the immune response and polarization
While there are conflicting data concerning interleukin (IL)-17 levels in the serum of patients
with leprosy compared with those in healthy controls, higher levels have been more evident …
with leprosy compared with those in healthy controls, higher levels have been more evident …
Presence of senescent and memory CD8+ leukocytes as immunocenescence markers in skin lesions of elderly leprosy patients
PHL Da Silva, KKG De Castro, MA Mendes… - Frontiers in …, 2021 - frontiersin.org
Leprosy is an infectious disease that remains endemic in approximately 100 develo**
countries, where about 200,000 new cases are diagnosed each year. Moreover …
countries, where about 200,000 new cases are diagnosed each year. Moreover …
[HTML][HTML] Central Nervous System Tuberculosis in a Murine Model: Neurotropic Strains or a New Pathway of Infection?
Tuberculosis (TB) of the central nervous system (CNS) is a lethal and incapacitating
disease. Several studies have been performed to understand the mechanism of bacterial …
disease. Several studies have been performed to understand the mechanism of bacterial …
Expression of FoxP3 in different forms of leprosy and reactions
Although regulatory T cells (Treg) are important in the immune regulation of various
pathological processes, the role of these cells in the immunology of leprosy still needs to be …
pathological processes, the role of these cells in the immunology of leprosy still needs to be …