Flowerbed-inspired biomimetic scaffold with rapid internal tissue infiltration and vascularization capacity for bone repair

X Zhou, Y Qian, L Chen, T Li, X Sun, X Ma, J Wang… - ACS …, 2023 - ACS Publications
The favorable microstructure and bioactivity of tissue-engineered bone scaffolds are closely
associated with the regenerative efficacy of bone defects. For the treatment of large bone …

Hydrogel drug delivery systems for bone regeneration

L Bai, G Tao, M Feng, Y **e, S Cai, S Peng, J **ao - Pharmaceutics, 2023 - mdpi.com
With the in-depth understanding of bone regeneration mechanisms and the development of
bone tissue engineering, a variety of scaffold carrier materials with desirable …

Exploring the potential of hydroxyapatite-based materials in biomedicine: A comprehensive review

C Liu, M Xu, Y Wang, Q Yin, J Hu, H Chen… - Materials Science and …, 2024 - Elsevier
Hydroxyapatite (HA), which shares similarities in both chemical composition and structure
with bone phosphate systems, and has garnered significant attention in biomedicine due to …

Glycopeptide‐Based Multifunctional Hydrogels Promote Diabetic Wound Healing through pH Regulation of Microenvironment

H **a, Z Dong, Q Tang, R Ding, Y Bai… - Advanced functional …, 2023 - Wiley Online Library
Excessive inflammation, bacterial infection, and blocked angiogenesis make diabetic wound
healing challenging. Multifunctional wound dressings have several advantages in diabetic …

Mild photothermal‐stimulation based on injectable and photocurable hydrogels orchestrates immunomodulation and osteogenesis for high‐performance bone …

M Wu, H Liu, Y Zhu, F Chen, Z Chen, L Guo, P Wu, G Li… - Small, 2023 - Wiley Online Library
A photoactivated bone scaffold integrated with minimally invasive implantation and mild
thermal‐stimulation capability shows great promise in the repair and regeneration of …

Remotely temporal scheduled macrophage phenotypic transition enables optimized immunomodulatory bone regeneration

D Huang, K Xu, X Huang, N Lin, Y Ye, S Lin, J Zhang… - Small, 2022 - Wiley Online Library
Precise timing of macrophage polarization plays a pivotal role in immunomodulation of
tissue regeneration, yet most studies mainly focus on M2 macrophages for their anti …

Bioinspired piezoelectric periosteum to augment bone regeneration via synergistic immunomodulation and osteogenesis

H Liu, Y Shi, Y Zhu, P Wu, Z Deng, Q Dong… - … Applied Materials & …, 2023 - ACS Publications
Ideal periosteum materials are required to participate in a sequence of bone repair-related
physiological events, including the initial immune response, endogenous stem cell …

nHA-loaded gelatin/alginate hydrogel with combined physical and bioactive features for maxillofacial bone repair

X Zhou, J Sun, K Wo, H Wei, H Lei, J Zhang, X Lu… - Carbohydrate …, 2022 - Elsevier
Critical-sized maxillofacial bone defects have been a tough clinical challenge considering
their requirements for functional and structural repair. In this study, an injectable in-situ …

Hyaluronic acid‐based reactive oxygen species‐responsive multifunctional injectable hydrogel platform accelerating diabetic wound healing

C Shi, Y Zhang, G Wu, Z Zhu, H Zheng… - Advanced …, 2024 - Wiley Online Library
Diabetic wounds are more likely to develop into complex and severe chronic wounds. The
objective of this study is to develop and assess a reactive oxygen species (ROS)‐responsive …

Bio-inspired glycosylated nano-hydroxyapatites enhance endogenous bone regeneration by modulating macrophage M2 polarization

D Qiao, S Cheng, Z **ng, Q Zhang, S Song, F Yan… - Acta Biomaterialia, 2023 - Elsevier
A macrophage-associated immune response is vital in bone regeneration. Mannose
receptor (MR), a macrophage pattern-recognition receptor, is crucial for the maintenance of …