[HTML][HTML] Pulmonary fibrosis: pathogenesis, etiology and regulation
Pulmonary fibrosis and architectural remodeling of tissues can severely disrupt lung
function, often with fatal consequences. The etiology of pulmonary fibrotic diseases is varied …
function, often with fatal consequences. The etiology of pulmonary fibrotic diseases is varied …
Annexin‐A1: a pivotal regulator of the innate and adaptive immune systems
The glucocorticoids are the most potent anti‐inflammatory drugs that we possess and are
effective in a wide variety of diseases. Although their action is known to involve receptor …
effective in a wide variety of diseases. Although their action is known to involve receptor …
Annexin-1 and peptide derivatives are released by apoptotic cells and stimulate phagocytosis of apoptotic neutrophils by macrophages
M Scannell, MB Flanagan, A destefani… - The Journal of …, 2007 - journals.aai.org
The resolution of inflammation is a dynamically regulated process that may be subverted in
many pathological conditions. Macrophage (Mφ) phagocytic clearance of apoptotic …
many pathological conditions. Macrophage (Mφ) phagocytic clearance of apoptotic …
Resolvin D1 reduces lung infection and inflammation activating resolution in cystic fibrosis
Non-resolving lung inflammation and Pseudomonas aeruginosa infections are the
underlying cause of morbidity and mortality in cystic fibrosis (CF). The endogenous lipid …
underlying cause of morbidity and mortality in cystic fibrosis (CF). The endogenous lipid …
Evidence of intestinal inflammation in patients with cystic fibrosis
SL Werlin, I Benuri-Silbiger, E Kerem… - Journal of pediatric …, 2010 - journals.lww.com
Objectives: Treatment with pancreatic enzymes fails to completely correct malabsorption and
gastrointestinal symptoms in patients with cystic fibrosis (CF). The aim of the present study …
gastrointestinal symptoms in patients with cystic fibrosis (CF). The aim of the present study …
Innate immune response in CF airway epithelia: hyperinflammatory?
TE Machen - American journal of physiology-cell …, 2006 - journals.physiology.org
The lack of functional cystic fibrosis (CF) transmembrane conductance regulator (CFTR) in
the apical membranes of CF airway epithelial cells abolishes cAMP-stimulated anion …
the apical membranes of CF airway epithelial cells abolishes cAMP-stimulated anion …
Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists
N Dufton, M Perretti - Pharmacology & therapeutics, 2010 - Elsevier
The need for novel anti-inflammatory drugs justifies the search for innovative targets that
could satisfy this goal. For quite some time now, we have proposed the study of endogenous …
could satisfy this goal. For quite some time now, we have proposed the study of endogenous …
Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia
Cystic fibrosis (CF) is caused by the functional expression defect of the CF transmembrane
conductance regulator (CFTR) chloride channel at the apical plasma membrane. Impaired …
conductance regulator (CFTR) chloride channel at the apical plasma membrane. Impaired …
Roles, actions, and therapeutic potential of specialized pro-resolving lipid mediators for the treatment of inflammation in cystic fibrosis
Non-resolving inflammation is the main mechanism of morbidity and mortality among
patients suffering from cystic fibrosis (CF), the most common life-threatening human genetic …
patients suffering from cystic fibrosis (CF), the most common life-threatening human genetic …
Airway epithelial cell inflammatory signalling in cystic fibrosis
J Jacquot, O Tabary, P Le Rouzic, A Clement - The international journal of …, 2008 - Elsevier
Cystic fibrosis (CF) is the most common lethal monogenic disorder in Caucasians, estimated
to affect one out of 2500–4000 new-borns. In patients with CF, lack of CF transmembrane …
to affect one out of 2500–4000 new-borns. In patients with CF, lack of CF transmembrane …