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Harnessing extracellular vesicle heterogeneity for diagnostic and therapeutic applications
Extracellular vesicles (EVs) are diverse nanoparticles with large heterogeneity in size and
molecular composition. Although this heterogeneity provides high diagnostic value for liquid …
molecular composition. Although this heterogeneity provides high diagnostic value for liquid …
A critical systematic review of extracellular vesicle clinical trials
This systematic review examines the landscape of extracellular vesicle (EV)‐related clinical
trials to elucidate the field's trends in clinical applications and EV‐related methodologies …
trials to elucidate the field's trends in clinical applications and EV‐related methodologies …
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …
origin and change the functions and phenotypes of other cells. These features indicate …
A beginner's guide to study extracellular vesicles in human blood plasma and serum
Blood is the most commonly used body fluid for obtaining and studying extracellular vesicles
(EVs). While blood is a standard choice for clinical analysis, using blood as a source of EVs …
(EVs). While blood is a standard choice for clinical analysis, using blood as a source of EVs …
Recommendations for reproducibility of cerebrospinal fluid extracellular vesicle studies
Cerebrospinal fluid (CSF) is a clear, transparent fluid derived from blood plasma that
protects the brain and spinal cord against mechanical shock, provides buoyancy, clears …
protects the brain and spinal cord against mechanical shock, provides buoyancy, clears …
Metabolism and HSC fate: what NADPH is made for
Mitochondrial metabolism plays a central role in the regulation of hematopoietic stem cell
(HSC) biology. Mitochondrial fatty acid oxidation (FAO) is pivotal in controlling HSC self …
(HSC) biology. Mitochondrial fatty acid oxidation (FAO) is pivotal in controlling HSC self …
Comparison of assays measuring extracellular vesicle tissue factor in plasma samples: communication from the ISTH SSC Subcommittee on Vascular Biology
Background Scientific and clinical interest in extracellular vesicles (EVs) is growing. EVs that
expose tissue factor (TF) bind factor VII/VIIa and can trigger coagulation. Highly …
expose tissue factor (TF) bind factor VII/VIIa and can trigger coagulation. Highly …
B cells secrete functional antigen-specific IgG antibodies on extracellular vesicles
C Rival, M Mandal, K Cramton, H Qiao, M Arish… - Scientific reports, 2024 - nature.com
B cells and the antibodies they produce are critical in host defense against pathogens and
contribute to various immune-mediated diseases. B cells responding to activating signals in …
contribute to various immune-mediated diseases. B cells responding to activating signals in …
Proteomic analysis of plasma-derived extracellular vesicles: Pre-and postprandial comparisons
Extracellular vesicles (EVs) are key in intercellular communication, carrying biomolecules
like nucleic acids, lipids, and proteins. This study investigated postprandial characteristics …
like nucleic acids, lipids, and proteins. This study investigated postprandial characteristics …
Droplets microfluidics platform—A tool for single cell research
B Li, X Ma, J Cheng, T Tian, J Guo, Y Wang… - … in Bioengineering and …, 2023 - frontiersin.org
Cells are the most basic structural and functional units of living organisms. Studies of cell
growth, differentiation, apoptosis, and cell-cell interactions can help scientists understand …
growth, differentiation, apoptosis, and cell-cell interactions can help scientists understand …