The control of male fertility by spermatozoan ion channels
PV Lishko, Y Kirichok, D Ren, B Navarro… - Annual review of …, 2012 - annualreviews.org
Ion channels control the sperm ability to fertilize the egg by regulating sperm maturation in
the female reproductive tract and by triggering key sperm physiological responses required …
the female reproductive tract and by triggering key sperm physiological responses required …
Sperm migration, selection, survival, and fertilizing ability in the mammalian oviduct
C Mahé, AM Zlotkowska, K Reynaud… - Biology of …, 2021 - academic.oup.com
In vitro fertilization (IVF) gives rise to embryos in a number of mammalian species and is
currently widely used for assisted reproduction in humans and for genetic purposes in cattle …
currently widely used for assisted reproduction in humans and for genetic purposes in cattle …
Progesterone activates the principal Ca2+ channel of human sperm
PV Lishko, IL Botchkina, Y Kirichok - Nature, 2011 - nature.com
Steroid hormone progesterone released by cumulus cells surrounding the egg is a potent
stimulator of human spermatozoa. It attracts spermatozoa towards the egg and helps them …
stimulator of human spermatozoa. It attracts spermatozoa towards the egg and helps them …
Mechanisms of sperm chemotaxis
Sperm are attracted by chemical factors that are released by the egg—a process called
chemotaxis. Most of our knowledge on sperm chemotaxis originates from the study of marine …
chemotaxis. Most of our knowledge on sperm chemotaxis originates from the study of marine …
Sperm processing for advanced reproductive technologies: Where are we today?
KL Rappa, HF Rodriguez, GC Hakkarainen… - Biotechnology …, 2016 - Elsevier
Assisted reproductive technologies (ARTs) utilize sperm sorting methods to select viable
sperm from the semen samples. Conventional sperm sorting techniques in current use are …
sperm from the semen samples. Conventional sperm sorting techniques in current use are …
[Ca2+]i signalling in sperm — making the most of what you've got
S Publicover, CV Harper, C Barratt - Nature cell biology, 2007 - nature.com
Thanks to a worrying decrease in male fertility, understanding how sperm'work'is a matter
both of interest and great importance. Sperm of all animals detect various environmental …
both of interest and great importance. Sperm of all animals detect various environmental …
Simulating nature in sperm selection for assisted reproduction
ETY Leung, CL Lee, X Tian, KKW Lam, RHW Li… - Nature Reviews …, 2022 - nature.com
Sperm selection in the female reproductive tract (FRT) is sophisticated. Only about 1,000
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …
Bend propagation in the flagella of migrating human sperm, and its modulation by viscosity
A pre‐requisite for sexual reproduction is successful unification of the male and female
gametes; in externally‐fertilising echinoderms the male gamete is brought into close …
gametes; in externally‐fertilising echinoderms the male gamete is brought into close …
Human sperm ion channel (dys) function: implications for fertilization
SG Brown, SJ Publicover, CLR Barratt… - Human reproduction …, 2019 - academic.oup.com
BACKGROUND Intensive research on sperm ion channels has identified members of
several ion channel families in both mouse and human sperm. Gene knock-out studies have …
several ion channel families in both mouse and human sperm. Gene knock-out studies have …
Ca2+ Signaling Tools Acquired from Prostasomes Are Required for Progesterone-Induced Sperm Motility
KH Park, BJ Kim, J Kang, TS Nam, JM Lim, HT Kim… - Science …, 2011 - science.org
Progesterone-induced calcium ion (Ca2+) signals in the neck region of sperm play a pivotal
role in promoting sperm motility. Here, we show that a long-lasting Ca2+ signal required for …
role in promoting sperm motility. Here, we show that a long-lasting Ca2+ signal required for …