Stimuli-responsive polymers can respond to internal stimuli, such as reactive oxygen
species (ROS), glutathione (GSH), and pH, biological stimuli, such as enzymes, and external …

Platinum-based drugs cisplatin, carboplatin, and oxaliplatin are widely used for
chemotherapeutic eradication of cancer. However, the side effects of platinum drugs, such …

Cancer thermal therapy, also known as hyperthermia therapy, has long been exploited to
eradicate mass lesions that are now defined as cancer. With the development of …

Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …

Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …

As one of the most important cancer treatment strategies, conventional chemotherapy has
substantial side effects and leads easily to cancer treatment failure. Therefore, exploring and …

Cancer cells frequently exhibit resistance to various molecular and nanoscale drugs, which
inevitably affects the drugs' therapeutic outcomes. Overexpression of glutathione (GSH) has …

Prodrugs are chemically modified drug molecules that are inactive before administration.
After administration, they are converted in situ to parent drugs and induce the mechanism of …

Platinum-based chemotherapy is widely used to treat various cancers. However, exogenous
platinum is likely to cause severe side effects and drug resistance induced by upregulated …

Although photothermal therapy (PTT) with the assistance of nanotechnology has been
considered as an indispensable strategy in the biomedical field, it still encounters some …