Extracellular vesicles (EVs) are a collective term for nanoscale or microscale vesicles
secreted by cells that play important biological roles. Mesenchymal stem cells are a class of …

Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are
nanosized membrane vesicles derived from most cell types. Carrying diverse biomolecules …

Understanding the molecular drivers and feedback loops of osteoarthritis (OA) may provide
future therapeutic strategies to modulate the disease progression. The current paradigm of …

Degenerative disorders of joints, especially osteoarthritis (OA), result in persistent pain and
disability and high costs to society. Nevertheless, the molecular mechanisms of OA have not …

Osteochondral defects are caused by injury to both the articular cartilage and subchondral
bone within skeletal joints. They can lead to irreversible joint damage and increase the risk …

Osteoarthritis (OA) is a prevalent chronic whole-joint disease characterized by low-grade
systemic inflammation, degeneration of joint-related tissues such as articular cartilage, and …

Mesenchymal stem cells (MSCs) are adult stem cells owing to their regenerative potential
and multilineage potency. MSCs have wide-scale applications either in their native cellular …

Emergent approaches in regenerative medicine look toward the use of extracellular vesicles
(EVs) as a next‐generation treatment strategy for intervertebral disc (IVD) degeneration …

The discovery that cells secrete extracellular vesicles (EVs), which carry a variety of
regulatory proteins, nucleic acids, and lipids, has shed light on the sophisticated manner by …

Background Skin wounding is very common and may be slow to heal. Increasing evidence
shows that exosomes derived from mesenchymal stem cells (MSCs) dramatically enhance …