The biological applications of DNA nanomaterials: current challenges and future directions

W Ma, Y Zhan, Y Zhang, C Mao, X **e… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

[HTML][HTML] Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis

M Zhao, R Wang, K Yang, Y Jiang, Y Peng, Y Li… - … Pharmaceutica Sinica B, 2023 - Elsevier
RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

[HTML][HTML] DNA tetrahedral nanostructures for the biomedical application and spatial orientation of biomolecules

W Wang, M Lin, W Wang, Z Shen, ZS Wu - Bioactive Materials, 2024 - Elsevier
DNA not only plays a vital role in nature as fundamental hereditary material for storing
genetic material, but also serves as well-defined functional material, for example, building …

Rationally engineered nucleic acid architectures for biosensing applications

M **ao, W Lai, T Man, B Chang, L Li… - Chemical …, 2019 - ACS Publications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

An Intelligent DNA Nanorobot with in Vitro Enhanced Protein Lysosomal Degradation of HER2

W Ma, Y Zhan, Y Zhang, X Shao, X **e, C Mao… - Nano …, 2019 - ACS Publications
DNA nanorobots have emerged as new tools for nanomedicine with the potential to
ameliorate the delivery and anticancer efficacy of various drugs. DNA nanostructures have …

Dual-SERS biosensor for one-step detection of microRNAs in exosome and residual plasma of blood samples for diagnosing pancreatic cancer

Y Pang, C Wang, LC Lu, C Wang, Z Sun… - Biosensors and …, 2019 - Elsevier
MicroRNAs have been proved to be the biomarker for early detection of pancreatic cancer
and the precisely quantitation of the MicroRNA-10b in the blood samples even can …

An electrochemical biosensor for simultaneous detection of breast cancer clinically related microRNAs based on a gold nanoparticles/graphene quantum dots …

C Pothipor, J Jakmunee, S Bamrungsap, K Ounnunkad - Analyst, 2021 - pubs.rsc.org
A label-free multiplexed electrochemical biosensor based on a gold nanoparticles/graphene
quantum dots/graphene oxide (AuNPs/GQDs/GO) modified three-screen-printed carbon …

Ultrasensitive detection of miRNA via CRISPR/Cas12a coupled with strand displacement amplification reaction

S Feng, H Chen, Z Hu, T Wu, Z Liu - ACS Applied Materials & …, 2023 - ACS Publications
MicroRNA (miRNA) is a promising biomarker for the diagnosis, monitoring, and prognostic
evaluation of diseases, especially cancer. The existing miRNA detection methods usually …

AND logic-gate-based CRISPR/Cas12a biosensing platform for the sensitive colorimetric detection of dual miRNAs

S Gong, X Wang, P Zhou, W Pan, N Li… - Analytical …, 2022 - ACS Publications
Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas (CRISPR-
associated) system has been widely explored for the detection of disease-related nucleic …

Ultrasensitive fluorescent miRNA biosensor based on a “sandwich” oligonucleotide hybridization and fluorescence resonance energy transfer process using an Ln (III) …

A Afzalinia, M Mirzaee - ACS applied materials & interfaces, 2020 - ACS Publications
Herein, a novel, rapid, highly sensitive, and selective fluorescent biosensor is presented,
which is designed based on “sandwich-type” hybridization of oligonucleotides and the …