The biological applications of DNA nanomaterials: current challenges and future directions

W Ma, Y Zhan, Y Zhang, C Mao, X **e… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

[HTML][HTML] Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis

M Zhao, R Wang, K Yang, Y Jiang, Y Peng, Y Li… - … Pharmaceutica Sinica B, 2023 - Elsevier
RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

Rationally engineered nucleic acid architectures for biosensing applications

M **ao, W Lai, T Man, B Chang, L Li… - Chemical …, 2019 - ACS Publications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

Dual-SERS biosensor for one-step detection of microRNAs in exosome and residual plasma of blood samples for diagnosing pancreatic cancer

Y Pang, C Wang, LC Lu, C Wang, Z Sun… - Biosensors and …, 2019 - Elsevier
MicroRNAs have been proved to be the biomarker for early detection of pancreatic cancer
and the precisely quantitation of the MicroRNA-10b in the blood samples even can …

An Intelligent DNA Nanorobot with in Vitro Enhanced Protein Lysosomal Degradation of HER2

W Ma, Y Zhan, Y Zhang, X Shao, X **e, C Mao… - Nano …, 2019 - ACS Publications
DNA nanorobots have emerged as new tools for nanomedicine with the potential to
ameliorate the delivery and anticancer efficacy of various drugs. DNA nanostructures have …

An electrochemical biosensor for simultaneous detection of breast cancer clinically related microRNAs based on a gold nanoparticles/graphene quantum dots …

C Pothipor, J Jakmunee, S Bamrungsap, K Ounnunkad - Analyst, 2021 - pubs.rsc.org
A label-free multiplexed electrochemical biosensor based on a gold nanoparticles/graphene
quantum dots/graphene oxide (AuNPs/GQDs/GO) modified three-screen-printed carbon …

Recent progresses in DNA nanostructure-based biosensors for detection of tumor markers

R Huang, N He, Z Li - Biosensors and Bioelectronics, 2018 - Elsevier
DNA has emerged as a promising biomaterial for assembling a variety of nanostructures
based on its programmable base pairing. It also has other remarkable properties including …

AND logic-gate-based CRISPR/Cas12a biosensing platform for the sensitive colorimetric detection of dual miRNAs

S Gong, X Wang, P Zhou, W Pan, N Li… - Analytical …, 2022 - ACS Publications
Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas (CRISPR-
associated) system has been widely explored for the detection of disease-related nucleic …

Electrochemical biosensors for detection of microRNA as a cancer biomarker: Pros and cons

M El Aamri, G Yammouri, H Mohammadi, A Amine… - Biosensors, 2020 - mdpi.com
Cancer is the second most fatal disease in the world and an early diagnosis is important for
a successful treatment. Thus, it is necessary to develop fast, sensitive, simple, and …

Ultrasensitive fluorescent miRNA biosensor based on a “sandwich” oligonucleotide hybridization and fluorescence resonance energy transfer process using an Ln (III) …

A Afzalinia, M Mirzaee - ACS applied materials & interfaces, 2020 - ACS Publications
Herein, a novel, rapid, highly sensitive, and selective fluorescent biosensor is presented,
which is designed based on “sandwich-type” hybridization of oligonucleotides and the …