Abstract The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …

A key element of contact lens practice involves clinical evaluation of anterior eye health,
including the cornea and limbus, conjunctiva and sclera, eyelids and eyelashes, lacrimal …

Goblet cells within the conjunctival epithelium are specialized cells that secrete mucins onto
the surface of the eye. Recent research has demonstrated new characteristics of the cells …

Mucins are key actors in tear film quality and tear film stability. Alteration of membrane-
bound mucin expression on corneal and conjunctival epithelial cells and/or gel-forming …

Great effort has been devoted to investigating the biodegradable composite fibrous
membranes (CFM) comprising polymer blends in single fiber via electrospinning. However …

The human ocular surface (front surface of the eye) is formed by two different types of
epithelia: the corneal epithelium centrally and the conjunctival epithelium that surrounds …

Wnt signaling comprises a group of complex signal transduction pathways that play critical
roles in cell proliferation, differentiation, and apoptosis during development, as well as in …

Dry eye disease (DED) is a prevalent chronic eye disease characterized by an aberrant
inflammatory response in ocular surface mucosa. The immunological alterations underlying …

Conjunctival goblet cells (CGCs) are specialized cells that produce and secrete soluble
mucins to the tear film that bathes the ocular surface. CGC numbers and functions are …

Ocular surface diseases including conjunctival disorders are multifactorial progressive
conditions that can severely affect vision and quality of life. In recent years, stem cell …