Twenty-five years of clinical applications using adaptive optics ophthalmoscopy
Twenty-five years ago, adaptive optics (AO) was combined with fundus photography,
thereby initiating a new era in the field of ophthalmic imaging. Since that time, clinical …
thereby initiating a new era in the field of ophthalmic imaging. Since that time, clinical …
Probing computation in the primate visual system at single-cone resolution
Daylight vision begins when light activates cone photoreceptors in the retina, creating
spatial patterns of neural activity. These cone signals are then combined and processed in …
spatial patterns of neural activity. These cone signals are then combined and processed in …
Modeling visual performance differences 'around'the visual field: A computational observer approach
Visual performance depends on polar angle, even when eccentricity is held constant; on
many psychophysical tasks observers perform best when stimuli are presented on the …
many psychophysical tasks observers perform best when stimuli are presented on the …
[HTML][HTML] A computational-observer model of spatial contrast sensitivity: Effects of wave-front-based optics, cone-mosaic structure, and inference engine
We present a computational-observer model of the human spatial contrast-sensitivity
function based on the Image Systems Engineering Toolbox for Biology (ISETBio) simulation …
function based on the Image Systems Engineering Toolbox for Biology (ISETBio) simulation …
Visual function at the atrophic border in choroideremia assessed with adaptive optics microperimetry
Purpose Recent advances in retinal imaging allow visualization of structural abnormalities in
retinal disease at the cellular level. This study used adaptive optics (AO) microperimetry to …
retinal disease at the cellular level. This study used adaptive optics (AO) microperimetry to …
Spatial summation of individual cones in human color vision
The human retina contains three classes of cone photoreceptors each sensitive to different
portions of the visual spectrum: long (L), medium (M) and short (S) wavelengths. Color …
portions of the visual spectrum: long (L), medium (M) and short (S) wavelengths. Color …
[HTML][HTML] The relationship between visual sensitivity and eccentricity, cone density and outer segment length in the human foveola
N Domdei, JL Reiniger, FG Holz… - … & Visual Science, 2021 - jov.arvojournals.org
Purpose: The cellular topography of the human foveola, the central 1 diameter of the fovea,
is strikingly non-uniform, with a steep increase of cone photoreceptor density and outer …
is strikingly non-uniform, with a steep increase of cone photoreceptor density and outer …
[HTML][HTML] Unique yellow shifts for small and brief stimuli in the central retina
The spectral locus of unique yellow was determined for flashes of different sizes (< 11
arcmin) and durations (< 500 ms) presented in and near the fovea. An adaptive optics …
arcmin) and durations (< 500 ms) presented in and near the fovea. An adaptive optics …
Repeatability and reciprocity of the cone optoretinogram
Optoretinography has enabled noninvasive visualization of physiological changes in cone
photoreceptors exposed to light. Understanding the cone optoretinogram in healthy subjects …
photoreceptors exposed to light. Understanding the cone optoretinogram in healthy subjects …
Extended-period AOSLO imaging in the living human retina without pupil dilation: a feasibility study
J Cui, M Villamil, AC Schneider, PF Lawton… - Biomedical Optics …, 2024 - opg.optica.org
In vivo imaging using an adaptive optics scanning laser ophthalmoscope (AOSLO) is
challenging, especially over extended periods. Pharmacological agents, administered as …
challenging, especially over extended periods. Pharmacological agents, administered as …