The vagus nerve in the neuro-immune axis: implications in the pathology of the gastrointestinal tract

B Bonaz, V Sinniger, S Pellissier - Frontiers in immunology, 2017 - frontiersin.org
The vagus nerve (VN) is the longest nerve of the organism and a major component of the
parasympathetic nervous system which constitutes the autonomic nervous system (ANS) …

Central nervous system control of gastrointestinal motility and secretion and modulation of gastrointestinal functions

KN Browning, RA Travagli - Comprehensive physiology, 2014 - pmc.ncbi.nlm.nih.gov
Although the gastrointestinal (GI) tract possesses intrinsic neural plexuses that allow a
significant degree of autonomy over GI functions, the central nervous system (CNS) provides …

Stress and the gut microbiota-brain axis

G Molina-Torres, M Rodriguez-Arrastia… - Behavioural …, 2019 - journals.lww.com
Stress is a nonspecific response of the body to any demand imposed upon it, disrupting the
body homoeostasis and manifested with symptoms such as anxiety, depression or even …

Corticotropin-releasing factor receptors and stress-related alterations of gut motor function

Y Taché, B Bonaz - The Journal of clinical investigation, 2007 - jci.org
Over the past few decades, corticotropin-releasing factor (CRF) signaling pathways have
been shown to be the main coordinators of the endocrine, behavioral, and immune …

Role of stress in functional gastrointestinal disorders: evidence for stress-induced alterations in gastrointestinal motility and sensitivity

H Mönnikes, JJ Tebbe, M Hildebrandt, P Arck… - Digestive …, 2001 - karger.com
Psychological stress is widely believed to play a major role in functional gastrointestinal (GI)
disorders, especially irritable bowel syndrome (IBS), by precipitating exacerbation of …

Irritable bowel syndrome, anxiety, and depression: what are the links?

RB Lydiard - Journal of Clinical Psychiatry, 2001 - psychiatrist.com
Irritable bowel syndrome (IBS) is a common and potentially disabling functional
gastrointestinal disorder characterized by abdominal pain and altered bowel patterns. A …

The lateral hypothalamic area revisited: ingestive behavior

LL Bernardis, LL Bellinger - Neuroscience & Biobehavioral Reviews, 1996 - Elsevier
This article discusses the role of the lateral hypothalamic area (LHA) in feeding and drinking
and draws on data obtained from lesion and stimulation studies and neurochemical and …

Effect of a corticotropin releasing hormone receptor antagonist on colonic sensory and motor function in patients with irritable bowel syndrome

Y Sagami, Y Shimada, J Tayama, T Nomura, M Satake… - Gut, 2004 - gut.bmj.com
Background and aims: Corticotropin releasing hormone (CRH) is a major mediator of the
stress response in the brain-gut axis. Irritable bowel syndrome (IBS) is presumed to be a …

Brain and gut CRF signaling: biological actions and role in the gastrointestinal tract

Y Tache, M Larauche, PQ Yuan… - Current molecular …, 2018 - benthamdirect.com
Background: Corticotropin-releasing factor (CRF) pathways coordinate behavioral,
endocrine, autonomic and visceral responses to stress. Convergent anatomical, molecular …

The role of CD4+ lymphocytes in the susceptibility of mice to stress-induced reactivation of experimental colitis

BS Qiu, BA Vallance, PA Blennerhassett, SM Collins - Nature medicine, 1999 - nature.com
Idiopathic inflammatory bowel disease is a chronic relapsing condition. The role of stress in
causing relapses of inflammatory bowel disease remains controversial. We now show that …