Antimicrobial resistance: more than 70 years of war between humans and bacteria

SF Nadeem, UF Gohar, SF Tahir… - Critical Reviews in …, 2020 - Taylor & Francis
Abstract Development of antibiotic resistance in bacteria is one of the major issues in the
present world and one of the greatest threats faced by mankind. Resistance is spread …

History of antibiotics research

KI Mohr - How to Overcome the Antibiotic Crisis: Facts …, 2016 - Springer
For thousands of years people were delivered helplessly to various kinds of infections,
which often reached epidemic proportions and have cost the lives of millions of people. This …

From oxiranes to oligomers: Architectures of US FDA approved pharmaceuticals containing oxygen heterocycles

MD Delost, DT Smith, BJ Anderson… - Journal of Medicinal …, 2018 - ACS Publications
Oxygen heterocycles are the second most common type of heterocycles that appear as
structural components of US Food and Drug Administration (FDA) approved …

Lincosamides: Chemical structure, biosynthesis, mechanism of action, resistance, and applications

J Spížek, T Řezanka - Biochemical pharmacology, 2017 - Elsevier
Lincomycin and its derivatives are antibiotics exhibiting biological activity against bacteria,
especially Gram-positive ones, and also protozoans. Lincomycin and its semi-synthetic …

Tetracycline-inactivating enzymes

JL Markley, TA Wencewicz - Frontiers in microbiology, 2018 - frontiersin.org
Tetracyclines have been foundational antibacterial agents for more than 70 years. Renewed
interest in tetracycline antibiotics is being driven by advancements in tetracycline synthesis …

The antibiotic resistome: what's new?

JA Perry, EL Westman, GD Wright - Current opinion in microbiology, 2014 - Elsevier
Highlights•The foundations of the antibiotic resistome were laid long before the introduction
of antibiotics into clinical practice.•Here, we update our theoretical framework for the …

From blood to regenerative tissue: how autologous platelet-rich fibrin can be combined with other materials to ensure controlled drug and growth factor release

K Egle, I Salma, A Dubnika - International journal of molecular sciences, 2021 - mdpi.com
The purpose of this review is to examine the latest literature on the use of autologous
platelet-rich fibrin as a drug and growth factor carrier system in maxillofacial surgery …

Lincosamides, streptogramins, phenicols, and pleuromutilins: mode of action and mechanisms of resistance

S Schwarz, J Shen, K Kadlec… - Cold Spring …, 2016 - perspectivesinmedicine.cshlp.org
Lincosamides, streptogramins, phenicols, and pleuromutilins (LSPPs) represent four
structurally different classes of antimicrobial agents that inhibit bacterial protein synthesis by …

Chelation in antibacterial drugs: From nitroxoline to cefiderocol and beyond

D Repac Antić, M Parčina, I Gobin, M Petković Didović - Antibiotics, 2022 - mdpi.com
In the era of escalating antimicrobial resistance, the need for antibacterial drugs with novel
or improved modes of action (MOAs) is a health concern of utmost importance. Adding or …

Alteration of gut microbiota after antibiotic exposure in finishing swine

HE Jo, MS Kwon, TW Whon, DW Kim, M Yun… - Frontiers in …, 2021 - frontiersin.org
Subclinical doses of antimicrobials are commonly used in the swine industry to control
infectious diseases and growth performance. Accumulating evidence suggests that swine …