PIWI-interacting RNAs (piRNAs) and their associated PIWI clade Argonaute proteins
constitute the core of the piRNA pathway. In gonadal cells, this conserved pathway is crucial …

The PIWI-interacting RNA (piRNA) pathway is a conserved defense mechanism that protects
the genetic information of animal germ cells from the deleterious effects of molecular …

Cytosine DNA methylation is a stable epigenetic mark that is crucial for diverse biological
processes, including gene and transposon silencing, imprinting and X chromosome …

PIWI-interacting RNAs (piRNAs) protect the animal germ line by silencing transposons.
Primary piRNAs, generated from transcripts of genomic transposon “junkyards”(piRNA …

In animal gonads, PIWI-clade Argonaute proteins repress transposons sequence-
specifically via bound Piwi-interacting RNAs (piRNAs). These are processed from single …

The spider mite Tetranychus urticae is a cosmopolitan agricultural pest with an extensive
host plant range and an extreme record of pesticide resistance. Here we present the …

To gain insight into how genomic information is translated into cellular and developmental
programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) …

Argonaute proteins of the PIWI clade are central to transposon silencing in animal gonads.
Their target specificity is defined by 23–30 nt PIWI interacting RNAs (piRNAs), which mostly …

Repetitive-element-derived Piwi-interacting RNAs (piRNAs), act together with Piwi proteins
Mili (also known as Piwil2) and Miwi2 (also known as Piwil4) in a genome defence …

In response to infection, invertebrates process replicating viral RNA genomes into siRNAs of
discrete sizes to guide virus clearance by RNA interference. Here, we show that viral siRNAs …