Advanced luminescent metal–organic framework (MOF) sensors engineered for urine analysis applications

B Mohan, RK Gupta, AJL Pombeiro, P Ren - Coordination Chemistry …, 2024 - Elsevier
Metal–organic frameworks (MOFs) have garnered attention in clinical sensing applications
due to their tailored structural and electronic properties, which facilitate the development of …

Programmed death receptor (PD-) 1/PD-ligand (L) 1 in urological cancers: the “all-around warrior” in immunotherapy

Q Liu, Y Guan, S Li - Molecular cancer, 2024 - Springer
Abstract Programmed death receptor-1 (PD-1) and its ligand, programmed death ligand-1
(PD-L1) are essential molecules that are key in modulating immune responses. PD-L1 is …

Mild magnetic hyperthermia-activated immuno-responses for primary bladder cancer therapy

F Qi, Q Bao, P Hu, Y Guo, Y Yan, X Yao, J Shi - Biomaterials, 2024 - Elsevier
Surgical intervention followed by chemotherapy is the principal treatment strategy for
bladder cancer, which is hindered by significant surgical risks, toxicity from chemotherapy …

Urinary markers for bladder cancer diagnosis: A review of current status and future challenges

E Tomiyama, K Fujita, M Hashimoto… - … Journal of Urology, 2024 - Wiley Online Library
Bladder cancer is a common urological cancer with a high recurrence rate that requires long‐
term follow‐up, and early detection positively affects prognosis. To date, the initial diagnosis …

Clinical effectiveness of a multitarget urine DNA test for urothelial carcinoma detection: a double-blinded, multicenter, prospective trial

J Wu, Y Lin, K Yang, X Liu, H Wang, T Yu, R Tao… - Molecular Cancer, 2024 - Springer
Urine-based testing is promising for noninvasive diagnosis of urothelial carcinoma (UC) but
has suboptimal sensitivity for early-stage tumors. Herein, we developed a multitarget urine …

Mini-review: current bladder cancer treatment—the need for improvement

E Gill, CM Perks - International Journal of Molecular Sciences, 2024 - mdpi.com
Bladder cancer is the tenth most common cancer and is a significant burden on health care
services worldwide, as it is one of the most costly cancers to treat per patient. This expense …

Using metabolomics and proteomics to identify the potential urine biomarkers for prediction and diagnosis of gestational diabetes

J Yu, J Ren, Y Ren, Y Wu, Y Zeng, Q Zhang, X **ao - EBioMedicine, 2024 - thelancet.com
Gestational diabetes mellitus (GDM) is one of the most common metabolic complications
during pregnancy, threatening both maternal and fetal health. Prediction and diagnosis of …

Synnotch-programmed macrophages for cancerous cell detection and sensing

T Wang, CH Lau, N Wang, J Li, J Wang, Z Huang… - ACS …, 2024 - ACS Publications
Synthetic Notch (synNotch) receptors have enabled mammalian cells to sense extracellular
ligands and respond by activating user-prescribed transcriptional programs. Based on the …

[HTML][HTML] Advanced bladder cancer detection: innovations in biomarkers and nanobiosensors

M Mousazadeh, M Nikkhah - Sensing and Bio-Sensing Research, 2024 - Elsevier
Bladder cancer is the 10th most common cancer and the 9th cause of death by malignancy
worldwide. Invasiveness and morbidity of cystoscopy, relatively low sensitivity of urinary …

[HTML][HTML] Prediction of clinically significant prostate Cancer by a specific collagen-related Transcriptome, Proteome, and Urinome signature

I Heidegger, M Frantzi, S Salcher, P Tymoszuk… - European Urology …, 2024 - Elsevier
Background and objective While collagen density has been associated with poor outcomes
in various cancers, its role in prostate cancer (PCa) remains elusive. Our aim was to analyze …