Ancient DNA damage
Under favorable conditions DNA can survive for thousands of years in the remains of dead
organisms. The DNA extracted from such remains is invariably degraded to a small average …
organisms. The DNA extracted from such remains is invariably degraded to a small average …
The future of ancient DNA: technical advances and conceptual shifts
Technological innovations such as next generation sequencing and DNA hybridisation
enrichment have resulted in multi‐fold increases in both the quantity of ancient DNA …
enrichment have resulted in multi‐fold increases in both the quantity of ancient DNA …
Population genomics of bronze age Eurasia
Abstract The Bronze Age of Eurasia (around 3000–1000 BC) was a period of major cultural
changes. However, there is debate about whether these changes resulted from the …
changes. However, there is debate about whether these changes resulted from the …
A high-coverage genome sequence from an archaic Denisovan individual
We present a DNA library preparation method that has allowed us to reconstruct a high-
coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The …
coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The …
Complete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragments
Although an inverse relationship is expected in ancient DNA samples between the number
of surviving DNA fragments and their length, ancient DNA sequencing libraries are strikingly …
of surviving DNA fragments and their length, ancient DNA sequencing libraries are strikingly …
Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse
The rich fossil record of equids has made them a model for evolutionary processes. Here we
present a 1.12-times coverage draft genome from a horse bone recovered from permafrost …
present a 1.12-times coverage draft genome from a horse bone recovered from permafrost …
Genomic and archaeological evidence suggest a dual origin of domestic dogs
The geographic and temporal origins of dogs remain controversial. We generated genetic
sequences from 59 ancient dogs and a complete (28x) genome of a late Neolithic dog …
sequences from 59 ancient dogs and a complete (28x) genome of a late Neolithic dog …
The half-life of DNA in bone: measuring decay kinetics in 158 dated fossils
Claims of extreme survival of DNA have emphasized the need for reliable models of DNA
degradation through time. By analysing mitochondrial DNA (mtDNA) from 158 radiocarbon …
degradation through time. By analysing mitochondrial DNA (mtDNA) from 158 radiocarbon …
Origins and genetic legacy of Neolithic farmers and hunter-gatherers in Europe
The farming way of life originated in the Near East some 11,000 years ago and had reached
most of the European continent 5000 years later. However, the impact of the agricultural …
most of the European continent 5000 years later. However, the impact of the agricultural …
AdapterRemoval: easy cleaning of next-generation sequencing reads
S Lindgreen - BMC research notes, 2012 - Springer
Background With the advent of next-generation sequencing there is an increased demand
for tools to pre-process and handle the vast amounts of data generated. One recurring …
for tools to pre-process and handle the vast amounts of data generated. One recurring …