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Therapy implications of hepatitis C virus genetic diversity
Hepatitis C virus (HCV) is an important human pathogen with a high chronicity rate. An
estimated 71 million people worldwide are living with chronic hepatitis C (CHC) infection …
estimated 71 million people worldwide are living with chronic hepatitis C (CHC) infection …
EASL recommendations on treatment of hepatitis C: final update of the series☆
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with
approximately 71 million chronically infected individuals worldwide. Clinical care for patients …
approximately 71 million chronically infected individuals worldwide. Clinical care for patients …
[HTML][HTML] Non-epidemic HCV genotypes in low-and middle-income countries and the risk of resistance to current direct-acting antiviral regimens
The hepatitis C virus (HCV) is an extremely diverse virus, subtypes of which are distributed
variably around the world. Viral genotypes may be divided into epidemic subtypes; those …
variably around the world. Viral genotypes may be divided into epidemic subtypes; those …
[HTML][HTML] Real-world effectiveness of voxilaprevir/velpatasvir/sofosbuvir in patients following DAA failure
C Graf, R D'Ambrosio, E Degasperi, S Paolucci… - JHEP Reports, 2024 - Elsevier
Background & Aims Voxilaprevir/velpatasvir/sofosbuvir (VOX/VEL/SOF) is highly effective for
re-treatment of direct-acting antiviral (DAA)-experienced patients with chronic HCV infection …
re-treatment of direct-acting antiviral (DAA)-experienced patients with chronic HCV infection …
'Unusual'HCV genotype subtypes: origin, distribution, sensitivity to direct-acting antiviral drugs and behaviour on antiviral treatment and retreatment
E Vo-Quang, JM Pawlotsky - Gut, 2024 - gut.bmj.com
The high genetic diversity of hepatitis C virus (HCV) has led to the emergence of eight
genotypes and a large number of subtypes in limited geographical areas. Currently …
genotypes and a large number of subtypes in limited geographical areas. Currently …
COVID-19, childhood obesity, and NAFLD: colliding pandemics
JB Moore - The Lancet Gastroenterology & Hepatology, 2022 - thelancet.com
The COVID-19 pandemic drastically affected the lives of children and young people
worldwide in 2020 and 2021. Public health measures to reduce community transmission of …
worldwide in 2020 and 2021. Public health measures to reduce community transmission of …
Identification of 2 novel subtypes of hepatitis C virus genotype 8 and a potential new genotype successfully treated with direct acting antivirals
Abstract Background Hepatitis C virus (HCV) has high genetic diversity and is classified into
8 genotypes and> 90 subtypes, with some endemic to specific world regions. This could …
8 genotypes and> 90 subtypes, with some endemic to specific world regions. This could …
Safety and efficacy of sofosbuvir–velpatasvir–voxilaprevir for re-treatment of chronic hepatitis C virus infection in patients with previous direct-acting antiviral treatment …
N Gupta, L Manirambona, F Shumbusho… - The Lancet …, 2022 - thelancet.com
Summary Background Hepatitis C virus (HCV) genotype 4 non-a/d subtypes, which
frequently have NS5A resistance-associated substitutions, are highly prevalent in sub …
frequently have NS5A resistance-associated substitutions, are highly prevalent in sub …
Prevalence of Drug Resistance Associated Substitutions in Persons With Chronic Hepatitis C Infection and Virological Failure Following Initial or Re-treatment With …
S Inzaule, P Easterbrook, A Latona… - Clinical Infectious …, 2024 - academic.oup.com
Background The advent of short-course, curative treatment with direct-acting antivirals (DAA)
has given promise for the global elimination of hepatitis C virus (HCV) infections by 2030 …
has given promise for the global elimination of hepatitis C virus (HCV) infections by 2030 …
[HTML][HTML] Genetic diversity of Hepatitis B and C viruses revealed by continuous surveillance from 2015 to 2021 in Gabon, Central Africa
H Abe, Y Ushijima, R Bikangui, GN Ondo, CM Pemba… - Microorganisms, 2023 - mdpi.com
Viral hepatitis remains one of the largest public health concerns worldwide. Especially in
Central Africa, information on hepatitis virus infections has been limited, although the …
Central Africa, information on hepatitis virus infections has been limited, although the …