Penicillium genus constituted by over 200 species is one of the largest and fascinating
groups of fungi, particularly well established as a source of antibiotics. Endophytic …

Paclitaxel (taxol), a diterpene natural compound was first extracted from the bark of yew
trees. However, the method cannot meet its increasing demand on the market due to …

Endophytes are the plant microorganisms that flourish inside plants (endosphere) and
support the growth under normal and challenging environmental circumstances. Besides …

The commercial production of paclitaxel; the most potent anti-cancer drug, is based on its
extraction from Taxus spp (yews) or microbial fermentation from yews' endophytes. The …

Millions of people are affected by neuronal disorders that are emerging as a principal cause
of death after cancer. Alzheimer's disease, ataxia, Parkinson's disease, multiple system …

Abstract Background Taxol, derived from Taxus trees, is a valuable natural resource for the
development of anticancer drugs. Endophytic fungi from Taxus trees are a promising …

From the last several years, there has been an increasing interest in plant-associated
bacteria commonly referred to as endophytes that reside asymptomatically in the internal …

Mountain biodiversity is under unparalleled pressure due to climate change, necessitating in-
depth research on high-altitude plant's microbial associations which are crucial for plant …

A complex network of interactions between fungal endophytes and their hosts results in
production of various kinds of primary and secondary metabolites. Research on enzymatic …

This work briefly reviews cancer chemoprevention. This is a very challenging field, as
products with a high level of toxicity such as chemotherapeutic agents may be proposed and …