Cognitive impairment (CI) is a characteristic non-motor feature of Parkinson disease (PD)
that poses a severe burden on the patients and caregivers, yet relatively little is known about …

Parkinson's disease is the second most common neurodegenerative disease, but
therapeutic options such as neuromodulation continue to show variable effects, making …

Background Reported orthostatic hypotension (OH) prevalence in Parkinson's disease (PD)
varies widely, with few studies evaluating specifically neurogenic-OH (nOH). The ratio of …

Orthostatic hypotension (OH) is more common in the elderly and associated with increased
mortality. However, its implications for 85-year-olds are not known. In the prospective …

Background Overwhelming evidence points to that genetic factors contributing to the
development of Alzheimer's disease (AD) and Parkinson's disease (PD). Genome-Wide …

The genetic basis of Neurogenic Orthostatic Hypotension (NOH) in Parkinson's disease (PD)
has been inadequately explored. In a cross-sectional study, we examined the association …

Background: Neurogenic orthostatic hypotension (NOH) is a significant non-motor
manifestation of Parkinson's disease (PD), that substantially affects patient disability and has …

Non-motor symptoms (NMS) occur in most people with Parkinson's disease (PD) during the
course of their disease and substantially affect function and quality of life 1–3 (Figs. 1–3) …

Background Orthostatic hypotension (OH) is a common symptom of multiple system atrophy
(MSA), however, its role in cognitive impairment and the mechanism in these patients …

Background Both measured orthostatic hypotension and symptomatic orthostasis are
common in PD but their relationship is unclear. Objective We aim to determine clinical …