Phospholipid membranes as chemically and functionally tunable materials

D Huster, S Maiti, A Herrmann - Advanced Materials, 2024 - Wiley Online Library
The sheet‐like lipid bilayer is the fundamental structural component of all cell membranes.
Its building blocks are phospholipids and cholesterol. Their amphiphilic structure …

The cubosome-based nanoplatforms in cancer therapy: Seeking new paradigms for cancer theranostics

BHJ Gowda, MG Ahmed, SA Alshehri, S Wahab… - Environmental …, 2023 - Elsevier
Lyotropic liquid crystals are self-assembled, non-lamellar, and mesophase nanostructured
materials that have garnered significant attention as drug carriers. Cubosomes, a subtype of …

Advancing therapeutic efficacy: nanovesicular delivery systems for medicinal plant-based therapeutics

MJ Saadh, MA Mustafa, S Kumar, P Gupta… - Naunyn-Schmiedeberg's …, 2024 - Springer
The utilization of medicinal plant extracts in therapeutics has been hindered by various
challenges, including poor bioavailability and stability issues. Nanovesicular delivery …

Lipid Nanoparticles: Versatile Drug Delivery Vehicles for Traversing the Blood Brain Barrier to Treat Brain Cancer

X Cai, CJ Drummond, J Zhai… - Advanced Functional …, 2024 - Wiley Online Library
The blood‐brain barrier (BBB) poses a significant challenge in delivering therapeutic agents
for brain diseases due to its high selectivity against foreign substances. This limitation …

Angiopep-2-Functionalized Lipid Cubosomes for Blood–Brain Barrier Crossing and Glioblastoma Treatment

X Cai, A Refaat, PY Gan, B Fan, H Yu… - … Applied Materials & …, 2024 - ACS Publications
Glioblastoma multiforme (GBM) is an aggressive brain cancer with high malignancy and
resistance to conventional treatments, resulting in a bleak prognosis. Nanoparticles offer a …

[HTML][HTML] Celecoxib-Loaded Cubosomal Nanoparticles as a Therapeutic Approach for Staphylococcus aureus In Vivo Infection

SZ Alshawwa, TA El-Masry, M Nasr, AY Kira… - Microorganisms, 2023 - mdpi.com
There is a great need for novel approaches to treating bacterial infections, due to the vast
dissemination of resistance among pathogenic bacteria. Staphylococcus aureus are …

[HTML][HTML] Box Behnken optimization of cubosomes for enhancing the anticancer activity of metformin: Design, characterization, and in-vitro cell proliferation assay on …

RM Zaki, LA Alkharashi, OM Sarhan… - International Journal of …, 2023 - Elsevier
This study aimed to formulate and statistically optimize cubosomal formulations of metformin
(MTF) to enhance its breast anticancer activity. A Box Behnken design was employed using …

[HTML][HTML] Current non-metal nanoparticle-based therapeutic approaches for glioblastoma treatment

AM Gawel, A Betkowska, E Gajda, M Godlewska… - Biomedicines, 2024 - mdpi.com
The increase in the variety of nano-based tools offers new possibilities to approach the
therapy of poorly treatable tumors, which includes glioblastoma multiforme (GBM; a primary …

[HTML][HTML] Innovative delivery and release systems for antioxidants and other active substances in the treatment of cancer

Z Sezgin-Bayindir, S Losada-Barreiro… - Pharmaceuticals, 2023 - mdpi.com
Cancer is one of the major diseases leading to death worldwide, and the fight against the
disease is still challenging. Cancer diseases are usually associated with increased oxidative …

[HTML][HTML] Advances in tailored drug delivery systems: Amphiphilic lyotropic mesomorphs for targeted therapeutic intervention

U Likhitha, UY Nayak - Journal of Molecular Liquids, 2024 - Elsevier
Amphiphilic molecules when dissolved in specific solvents form lyotropic mesomorphs with
unique crystalline structures and properties. The amphiphilic nature and supramolecular …