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Phospholipid membranes as chemically and functionally tunable materials
The sheet‐like lipid bilayer is the fundamental structural component of all cell membranes.
Its building blocks are phospholipids and cholesterol. Their amphiphilic structure …
Its building blocks are phospholipids and cholesterol. Their amphiphilic structure …
The cubosome-based nanoplatforms in cancer therapy: Seeking new paradigms for cancer theranostics
Lyotropic liquid crystals are self-assembled, non-lamellar, and mesophase nanostructured
materials that have garnered significant attention as drug carriers. Cubosomes, a subtype of …
materials that have garnered significant attention as drug carriers. Cubosomes, a subtype of …
Advancing therapeutic efficacy: nanovesicular delivery systems for medicinal plant-based therapeutics
The utilization of medicinal plant extracts in therapeutics has been hindered by various
challenges, including poor bioavailability and stability issues. Nanovesicular delivery …
challenges, including poor bioavailability and stability issues. Nanovesicular delivery …
Lipid Nanoparticles: Versatile Drug Delivery Vehicles for Traversing the Blood Brain Barrier to Treat Brain Cancer
The blood‐brain barrier (BBB) poses a significant challenge in delivering therapeutic agents
for brain diseases due to its high selectivity against foreign substances. This limitation …
for brain diseases due to its high selectivity against foreign substances. This limitation …
Angiopep-2-Functionalized Lipid Cubosomes for Blood–Brain Barrier Crossing and Glioblastoma Treatment
Glioblastoma multiforme (GBM) is an aggressive brain cancer with high malignancy and
resistance to conventional treatments, resulting in a bleak prognosis. Nanoparticles offer a …
resistance to conventional treatments, resulting in a bleak prognosis. Nanoparticles offer a …
[HTML][HTML] Celecoxib-Loaded Cubosomal Nanoparticles as a Therapeutic Approach for Staphylococcus aureus In Vivo Infection
There is a great need for novel approaches to treating bacterial infections, due to the vast
dissemination of resistance among pathogenic bacteria. Staphylococcus aureus are …
dissemination of resistance among pathogenic bacteria. Staphylococcus aureus are …
[HTML][HTML] Box Behnken optimization of cubosomes for enhancing the anticancer activity of metformin: Design, characterization, and in-vitro cell proliferation assay on …
This study aimed to formulate and statistically optimize cubosomal formulations of metformin
(MTF) to enhance its breast anticancer activity. A Box Behnken design was employed using …
(MTF) to enhance its breast anticancer activity. A Box Behnken design was employed using …
[HTML][HTML] Current non-metal nanoparticle-based therapeutic approaches for glioblastoma treatment
AM Gawel, A Betkowska, E Gajda, M Godlewska… - Biomedicines, 2024 - mdpi.com
The increase in the variety of nano-based tools offers new possibilities to approach the
therapy of poorly treatable tumors, which includes glioblastoma multiforme (GBM; a primary …
therapy of poorly treatable tumors, which includes glioblastoma multiforme (GBM; a primary …
[HTML][HTML] Innovative delivery and release systems for antioxidants and other active substances in the treatment of cancer
Z Sezgin-Bayindir, S Losada-Barreiro… - Pharmaceuticals, 2023 - mdpi.com
Cancer is one of the major diseases leading to death worldwide, and the fight against the
disease is still challenging. Cancer diseases are usually associated with increased oxidative …
disease is still challenging. Cancer diseases are usually associated with increased oxidative …
[HTML][HTML] Advances in tailored drug delivery systems: Amphiphilic lyotropic mesomorphs for targeted therapeutic intervention
Amphiphilic molecules when dissolved in specific solvents form lyotropic mesomorphs with
unique crystalline structures and properties. The amphiphilic nature and supramolecular …
unique crystalline structures and properties. The amphiphilic nature and supramolecular …