The bioavailability of drugs—the current state of knowledge
M Stielow, A Witczyńska, N Kubryń, Ł Fijałkowski… - Molecules, 2023 - mdpi.com
Drug bioavailability is a crucial aspect of pharmacology, affecting the effectiveness of drug
therapy. Understanding how drugs are absorbed, distributed, metabolized, and eliminated in …
therapy. Understanding how drugs are absorbed, distributed, metabolized, and eliminated in …
[HTML][HTML] Efficient synthesis of new azo-sulfonamide derivatives and investigation of their molecular docking and cytotoxicity results
The present study focused on the synthesis, introduction and investigation of the biological
effects of sulfonamide-derived products as new azo-sulfonamides (samples 1–6). In this …
effects of sulfonamide-derived products as new azo-sulfonamides (samples 1–6). In this …
Integrating Nanotechnological Advancements of Disease-Modifying Anti-Rheumatic Drugs into Rheumatoid Arthritis Management
S Singh, N Tiwary, N Sharma, T Behl, A Antil… - Pharmaceuticals, 2024 - mdpi.com
Disease-modifying anti-rheumatic drugs (DMARDs) is a class of anti-rheumatic medicines
that are frequently prescribed to patients suffering from rheumatoid arthritis (RA) …
that are frequently prescribed to patients suffering from rheumatoid arthritis (RA) …
A comparison between optimized PLGA and CS-Alg-PLGA microspheres for long-lasting release of glatiramer acetate
Abstract Glatiramer acetate (GA, Copaxone, COP, Copolymer-1) is one of the most
prescribed drugs to treat relapsing-remitting multiple sclerosis (RRMS). Herein, the formula …
prescribed drugs to treat relapsing-remitting multiple sclerosis (RRMS). Herein, the formula …
Synergistic cytotoxicity of olive leaf extract-loaded lipid nanocarriers combined with Newcastle disease virus against cervical cancer cells
A Golalipour, A Mohammadi, S Hosseinzadeh… - Plos one, 2024 - journals.plos.org
Despite recent medical progress, cervical cancer remains a major global health concern for
women. Current standard treatments have limitations such as non-specific toxicity that …
women. Current standard treatments have limitations such as non-specific toxicity that …
[HTML][HTML] Formulation of Glibenclamide proniosomes for oral administration: Pharmaceutical and pharmacodynamics evaluation
Glibenclamide (GB), oral antidiabetic sulfonylurea, is used in the management of diabetes
mellitus type II. It suffers from low bioavailability due to low water solubility. This work aimed …
mellitus type II. It suffers from low bioavailability due to low water solubility. This work aimed …
Quality by Design (QbD) enabled and Box-Behnken design assisted approach for formulation of tranexamic acid loaded stratum corneum lipid liposomes
Tranexamic acid, a highly hydrophilic drug, is used for treatment of hyperpigmentation but
topical delivery of drug is limited by poor permeation across lipidic stratum corneum …
topical delivery of drug is limited by poor permeation across lipidic stratum corneum …
Theoretical and experimental studies on sulfasalazine interactions with poly (lactic acid): Impact of hydrogen bonding and charge transfer interactions on molecular …
AN Safa, A Sheibani, MT Baei, SZ Sayyed-Alangi… - Heliyon, 2024 - cell.com
The interaction between sulfasalazine (SSZ) through different functional groups and poly
(lactic acid)(PLA) in the chloroform phase was investigated in this study using density …
(lactic acid)(PLA) in the chloroform phase was investigated in this study using density …
Experimental and theoretical studies on the interaction of finasteride with chitosan-based nanoniosomes
This research is aimed to develop a novel finasteride (FIN) release system based on
chitosan-based nanoniosomes (CS-Nio) by thin-film hydration method. The particle size …
chitosan-based nanoniosomes (CS-Nio) by thin-film hydration method. The particle size …
Glutathione-modified hyaluronic acid nanoparticles for the targeted delivery of sulfasalazine to neuroblastoma
M Kasprzyk, A Hinz, M Bzowska, D Lachowicz… - European Polymer …, 2024 - Elsevier
A new nanoparticulate system based on hyaluronic acid for targeted delivery of
sulfasalazine (SSA) to neuroblastoma was synthetized and characterized. The SSA …
sulfasalazine (SSA) to neuroblastoma was synthetized and characterized. The SSA …