Biochemical and mechanical regulation of actin dynamics

P Lappalainen, T Kotila, A Jégou… - … Reviews Molecular Cell …, 2022 - nature.com
Polymerization of actin filaments against membranes produces force for numerous cellular
processes, such as migration, morphogenesis, endocytosis, phagocytosis and organelle …

Self-assembled stereomutation with supramolecular chirality inversion

G Liu, MG Humphrey, C Zhang, Y Zhao - Chemical Society Reviews, 2023 - pubs.rsc.org
Supramolecular chirality is involved not only in biological events such as gene
communication, replication, and enzyme catalysis but also in artificial self-assembly systems …

Stereospecific interactions between chiral inorganic nanomaterials and biological systems

X Zhao, SQ Zang, X Chen - Chemical Society Reviews, 2020 - pubs.rsc.org
Chirality is ubiquitous in nature and plays mysterious and essential roles in maintaining key
biological and physiological processes. As biological systems display high selectivity for …

Creating complex protocells and prototissues using simple DNA building blocks

N Arulkumaran, M Singer, S Howorka… - Nature …, 2023 - nature.com
Building synthetic protocells and prototissues hinges on the formation of biomimetic skeletal
frameworks. Recreating the complexity of cytoskeletal and exoskeletal fibers, with their …

Spontaneous shear flow in confined cellular nematics

G Duclos, C Blanch-Mercader, V Yashunsky… - Nature physics, 2018 - nature.com
In embryonic development or tumour evolution, cells often migrate collectively within
confining tracks defined by their microenvironment,. In some of these situations, the …

Investigating chiral morphogenesis of gold using generative cellular automata

SW Im, D Zhang, JH Han, RM Kim, C Choi, YM Kim… - Nature Materials, 2024 - nature.com
Homochirality is an important feature in biological systems and occurs even in inorganic
nanoparticles. However, the mechanism of chirality formation and the key steps during …

Mechanical regulation of early vertebrate embryogenesis

M Valet, ED Siggia, AH Brivanlou - Nature Reviews Molecular Cell …, 2022 - nature.com
Embryonic cells grow in environments that provide a plethora of physical cues, including
mechanical forces that shape the development of the entire embryo. Despite their …

Cell response to substrate rigidity is regulated by active and passive cytoskeletal stress

BL Doss, M Pan, M Gupta, G Grenci, RM Mège… - Proceedings of the …, 2020 - pnas.org
Morphogenesis, tumor formation, and wound healing are regulated by tissue rigidity. Focal
adhesion behavior is locally regulated by stiffness; however, how cells globally adapt …

Stimulation of neural stem cell differentiation by circularly polarized light transduced by chiral nanoassemblies

A Qu, M Sun, JY Kim, L Xu, C Hao, W Ma… - Nature Biomedical …, 2021 - nature.com
The biological effects of circularly polarized light on living cells are considered to be
negligibly weak. Here, we show that the differentiation of neural stem cells into neurons can …

Steps in mechanotransduction pathways that control cell morphology

H Wolfenson, B Yang, MP Sheetz - Annual review of physiology, 2019 - annualreviews.org
It is increasingly clear that mechanotransduction pathways play important roles in regulating
fundamental cellular functions. Of the basic mechanical functions, the determination of …