Environmental factors are important regulators of cell growth and proliferation. Mechanistic
target of rapamycin (mTOR) is a central kinase that maintains cellular homeostasis in …

Simple Summary Apolipoproteins (APOs) are crucial components in our blood that are
responsible for fat management. Recent scientific discoveries suggest a provocative link …

Aim: Colorectal cancer (CRC) is the leading cause of cancer associated death worldwide
and immune checkpoint blockade therapy only benefit a small set of CRC patients. Tumor …

Dramatic improvements in cancer survival have occurred in the last decade, but the quality
of life for many survivors is compromised due to severe, long-lasting, and often irreversible …

The physical and functional interaction between transient receptor potential channel ankyrin
1 (TRPA1) and neuronal calcium sensor 1 (NCS-1) was assessed. NCS-1 is a calcium …

The discovery that apolipoprotein L1 (APOL1) is the trypanolytic factor of human serum
raised interest about the function of APOLs, especially following the unexpected finding that …

With the essential role of lipid transporting signaling in cancer‐related immunity,
apolipoprotein L3 (APOL3), a member of the apolipoprotein L gene family, demonstrated …

Abstract Calcium (Ca2+) signaling is critical for neuronal functioning and requires the
concerted interplay of numerous Ca2+‐binding proteins, including neuronal calcium sensor …

Changes in intracellular calcium (Ca2+) signaling can modulate cellular machinery required
for cancer progression. Neuronal calcium sensor 1 (NCS1) is a ubiquitously expressed …

Inositol 1, 4, 5-trisphosphate receptors (InsP3Rs) are endoplasmic reticulum–localized
channels that mediate Ca 2+ release from the endoplasmic reticulum into the cytoplasm. We …