Small animal PET: a review of what we have done and where we are going

RS Miyaoka, AL Lehnert - Physics in Medicine & Biology, 2020 - iopscience.iop.org
Small animal research is an essential tool in studying both pharmaceutical biodistribution
and disease progression over time. Furthermore, through the rapid development of in vivo …

Medical applications of silicon photomultipliers

MG Bisogni, A Del Guerra, N Belcari - Nuclear instruments and methods in …, 2019 - Elsevier
Silicon photomultipliers (SiPMs) are becoming the reference photodetectors in many fields.
In medicine they are slowly replacing photomultiplier tubes and avalanche photodiodes in …

Expression of the excitatory opsin ChRERα can be traced longitudinally in rat and nonhuman primate brains with PET imaging

J Bonaventura, MA Boehm, HP Jedema… - Science translational …, 2023 - science.org
Optogenetics is a widely used technology with potential for translational research. A critical
component of such applications is the ability to track the location of the transduced opsin in …

Performance comparison of dual-ended readout depth-encoding PET detectors based on BGO and LYSO crystals

J Du, G Ariño-Estrada, X Bai… - Physics in Medicine & …, 2020 - iopscience.iop.org
The performance of dual-ended readout depth-encoding positron emission tomography
(PET) detectors based on bismuth germanate (BGO) coupled to silicon photomultipliers …

Performance comparison of two signal multiplexing readouts for SiPM-based pet detector

Q Yang, Z Kuang, Z Sang, Y Yang… - Physics in Medicine & …, 2019 - iopscience.iop.org
PET scanners using SiPMs as photodetectors could have tens of thousands of SiPMs. To
simplify the readout electronics, analog signal multiplexing readouts are always preferred to …

H2RSPET: a 0.5 mm resolution high-sensitivity small-animal PET scanner, a simulation study

Y Lai, Q Wang, S Zhou, Z ** a total-body small-animal PET system with a high spatial
resolution of∼ 0.5 mm and a high sensitivity> 10% for mouse/rat studies, we simulated four …

Technical opportunities and challenges in develo** total-body PET scanners for mice and rats

J Du, T Jones - EJNMMI physics, 2023 - Springer
Positron emission tomography (PET) is the most sensitive in vivo molecular imaging
technique available. Small animal PET has been widely used in studying pharmaceutical …

Performance comparison of depth-encoding detectors based on dual-ended readout and different SiPMs for high-resolution PET applications

J Du, X Bai, SR Cherry - Physics in Medicine & Biology, 2019 - iopscience.iop.org
Silicon photomultipliers (SiPMs) are widely used in positron emission tomography (PET),
however, SiPMs from different vendors vary in their performance characteristics. In addition …

[HTML][HTML] Position-sensitive silicon photomultiplier arrays with large-area and sub-millimeter resolution

F Acerbi, S Merzi, A Gola - Sensors, 2024 - mdpi.com
Silicon photomultipliers (SiPMs) are solid-state single-photon-sensitive detectors that show
excellent performance in a wide range of applications. In FBK (Trento, Italy), we developed a …

A digital phoswich detector using time-over-threshold for depth of interaction in PET

DL Prout, Z Gu, M Shustef… - Physics in Medicine & …, 2020 - iopscience.iop.org
We present the performance of a digital phoswich positron emission tomography (PET)
detector, composed by layers of pixilated scintillator arrays, read out by solid state light …