Novel 5-alkenylthiothiazolidinone scaffold discovery as Multi-Chitinases inhibitors to arrest the molting of Asian corn borer

D Shi, X Ji, R Zou, Z Jiang, Y Duan, Q Han, Z Xu… - Journal of Molecular …, 2025 - Elsevier
Chitinases are crucial enzymes in insect growth and development processes and have thus
become potential targets for the control of insect pests. Rhodanine (5 …

Design, Synthesis, Computational Investigations, and Antitumor Evaluation of N-Rhodanine Glycosides Derivatives as Potent DNA Intercalation and Topo II Inhibition …

AI Khodair, FM Alzahrani, MK Awad, SA Al-Issa… - ACS …, 2023 - ACS Publications
Nitrogen and sulfur glycosylation was carried out via the reaction of rhodanine (1) with α-
acetobromoglucose 3 under basic conditions. Deacetylation of the protected nitrogen …

Discovery of novel dihydro-pyrimidine hybrids: insight into the design, synthesis, biological evaluation and absorption, distribution, metabolism and excretion studies

U Arshad, N Shafiq, S Parveen… - Future Medicinal …, 2024 - Taylor & Francis
Aim: By kee** in aspects, the pharmacological potential of heterocyclic compounds,
pyrimidine-based compounds were designed, synthesized and evaluated for α-amylase …

结合容错编码的量子化学分布式计算

**宁, 徐丽娜, 方国勇, 马英晋 - 化学学报, 2024 - sioc-journal.cn
摘要随着大尺度模拟, 机器学**等前沿应用的兴起, 分布式计算越发成为重要的计算研究手段.
然而分布式计算由于多节点导致的软硬件局限, 在科学计算, 机器学**等领域的应用仍会存在 …