Patterning the vertebrate neuraxis
A Lumsden, R Krumlauf - Science, 1996 - science.org
Neuraxial patterning is a continuous process that extends over a protracted period of
development. During gastrulation a crude anteroposterior pattern, detectable by molecular …
development. During gastrulation a crude anteroposterior pattern, detectable by molecular …
Gynecologic cancers and non-coding RNAs: epigenetic regulators with emerging roles
Gynecologic cancers involve the female genital organs, such as the vulva, vagina, cervix,
endometrium, ovaries, and fallopian tubes. The occurrence and frequency of gynecologic …
endometrium, ovaries, and fallopian tubes. The occurrence and frequency of gynecologic …
Segmentation and patterning of the vertebrate hindbrain
R Krumlauf, DG Wilkinson - Development, 2021 - journals.biologists.com
During early development, the hindbrain is sub-divided into rhombomeres that underlie the
organisation of neurons and adjacent craniofacial tissues. A gene regulatory network of …
organisation of neurons and adjacent craniofacial tissues. A gene regulatory network of …
Transcriptional Regulation and Implications for Controlling Hox Gene Expression
Z Afzal, R Krumlauf - Journal of Developmental Biology, 2022 - mdpi.com
Hox genes play key roles in axial patterning and regulating the regional identity of cells and
tissues in a wide variety of animals from invertebrates to vertebrates. Nested domains of Hox …
tissues in a wide variety of animals from invertebrates to vertebrates. Nested domains of Hox …
[HTML][HTML] Coupling the roles of Hox genes to regulatory networks patterning cranial neural crest
HJ Parker, I Pushel, R Krumlauf - Developmental biology, 2018 - Elsevier
The neural crest is a transient population of cells that forms within the develo** central
nervous system and migrates away to generate a wide range of derivatives throughout the …
nervous system and migrates away to generate a wide range of derivatives throughout the …
Hox genes: Downstream “effectors” of retinoic acid signaling in vertebrate embryogenesis
C Nolte, B De Kumar, R Krumlauf - genesis, 2019 - Wiley Online Library
One of the major regulatory challenges of animal development is to precisely coordinate in
space and time the formation, specification, and patterning of cells that underlie elaboration …
space and time the formation, specification, and patterning of cells that underlie elaboration …
circEIF4G2 modulates the malignant features of cervical cancer via the miR‑218/HOXA1 pathway
Y Mao, L Zhang, Y Li - Molecular Medicine Reports, 2019 - spandidos-publications.com
Circular RNAs (circRNAs) serve important roles in tumorigenesis and may be used as novel
molecular biomarkers for clinical diagnosis. However, the role and molecular mechanisms of …
molecular biomarkers for clinical diagnosis. However, the role and molecular mechanisms of …
A Hox gene regulatory network for hindbrain segmentation
HJ Parker, R Krumlauf - Current topics in developmental biology, 2020 - Elsevier
In vertebrates, the hindbrain serves as a highly conserved complex coordination center for
regulating many fundamental activities of the central nervous system, such as respiratory …
regulating many fundamental activities of the central nervous system, such as respiratory …
A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates
In jawed vertebrates (gnathostomes), Hox genes play an important role in patterning head
and jaw formation, but mechanisms coupling Hox genes to neural crest (NC) are unknown …
and jaw formation, but mechanisms coupling Hox genes to neural crest (NC) are unknown …
A conserved HOTAIRM1-HOXA1 regulatory axis contributes early to neuronal differentiation
D Segal, S Coulombe, J Sim, J Dostie - RNA biology, 2023 - Taylor & Francis
ABSTRACT HOTAIRM1 is unlike most long non-coding RNAs in that its sequence is highly
conserved across mammals. Such evolutionary conservation points to it having a role in key …
conserved across mammals. Such evolutionary conservation points to it having a role in key …