Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Dry eye disease (DED) is a multifactorial condition affecting the ocular surface. It is
characterized by loss of tear film homeostasis and accompanied by ocular symptoms that …

Corneal alkali burns represent a prevalent ophthalmic emergency with the potential to
induce blindness. The main contributing mechanisms include excessive inflammation and …

Dry eye disease (DED) affects a substantial worldwide population with increasing frequency.
Current single-targeting DED management is severely hindered by the existence of an …

Dry eye disease (DED) is associated with ocular hyperosmolarity and inflammation. The
marketed topical eye drops for DED treatment often lack bioavailability and precorneal …

Owing to the variety and complexity of ocular diseases and the natural ocular barriers, drug
therapy for ocular diseases has significant limitations, such as poor drug targeting to the site …

Inflammatory dysregulation is intimately associated with the occurrence and progression of
many life-threatening diseases. Accurate detection and timely therapeutic intervention on …

Uveitis is a complex ocular inflammatory disease with a multifactorial etiology that can result
in blindness. Although corticosteroid eye drops are the primary treatment for anterior uveitis …

Transition metal ions are served as disinfectant thousand years ago. However, the in vivo
antibacterial application of metal ions is strongly restricted due to its high affinity with …

Bioactive compound intervention of dry eye disease has been considered as a promising
approach due to the lower adverse reactions. In this study, layer-by-layer oral-deliverable …