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Copper homeostasis and cuproptosis in health and disease
L Chen, J Min, F Wang - Signal transduction and targeted therapy, 2022 - nature.com
As an essential micronutrient, copper is required for a wide range of physiological processes
in virtually all cell types. Because the accumulation of intracellular copper can induce …
in virtually all cell types. Because the accumulation of intracellular copper can induce …
Ironing out the role of ferroptosis in immunity
Ferroptosis is a type of regulated cell death that drives the pathophysiology of many
diseases. Oxidative stress is detectable in many types of regulated cell death, but only …
diseases. Oxidative stress is detectable in many types of regulated cell death, but only …
Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases
Y Wang, J Hu, S Wu, JS Fleishman, Y Li, Y Xu… - Signal transduction and …, 2023 - nature.com
Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
[HTML][HTML] Ferroptosis in health and disease
Ferroptosis is a pervasive non-apoptotic form of cell death highly relevant in various
degenerative diseases and malignancies. The hallmark of ferroptosis is uncontrolled and …
degenerative diseases and malignancies. The hallmark of ferroptosis is uncontrolled and …
Iron imbalance in neurodegeneration
Iron is an essential element for the development and functionality of the brain, and
anomalies in its distribution and concentration in brain tissue have been found to be …
anomalies in its distribution and concentration in brain tissue have been found to be …
The neuropathobiology of multiple sclerosis
Chronic low-grade inflammation and neuronal deregulation are two components of a
smoldering disease activity that drives the progression of disability in people with multiple …
smoldering disease activity that drives the progression of disability in people with multiple …
Ferroptosis: principles and significance in health and disease
Ferroptosis, an iron-dependent form of cell death characterized by uncontrolled lipid
peroxidation, is governed by molecular networks involving diverse molecules and …
peroxidation, is governed by molecular networks involving diverse molecules and …
The mechanism of ferroptosis and its related diseases
S Feng, D Tang, Y Wang, X Li, H Bao, C Tang… - Molecular …, 2023 - Springer
Ferroptosis, a regulated form of cellular death characterized by the iron-mediated
accumulation of lipid peroxides, provides a novel avenue for delving into the intersection of …
accumulation of lipid peroxides, provides a novel avenue for delving into the intersection of …
Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression
E Van San, AC Debruyne, G Veeckmans… - Cell Death & …, 2023 - nature.com
Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by central nervous
(CNS) demyelination resulting in axonal injury and neurological deficits. Essentially, MS is …
(CNS) demyelination resulting in axonal injury and neurological deficits. Essentially, MS is …
[HTML][HTML] Research on ferroptosis as a therapeutic target for the treatment of neurodegenerative diseases
Y Wang, M Lv, W Zhao - Ageing research reviews, 2023 - Elsevier
Ferroptosis is an iron-and lipid peroxidation (LPO)-mediated programmed cell death type.
Recently, mounting evidence has indicated the involvement of ferroptosis in …
Recently, mounting evidence has indicated the involvement of ferroptosis in …