Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …

Increased efforts in antimalarial drug discovery are urgently needed. The goal must be to
develop safe and affordable new drugs to counter the spread of malaria parasites that are …

Genome manipulation in the malaria parasite Plasmodium falciparum remains largely
intractable and improved genomic tools are needed to further understand pathogenesis and …

The dry season is a major challenge for Plasmodium falciparum parasites in many malaria
endemic regions, where water availability limits mosquito vectors to only part of the year …

During the blood stages of malaria, several hundred parasite-encoded proteins are exported
beyond the double-membrane barrier that separates the parasite from the host cell …

To mediate its survival and virulence, the malaria parasite Plasmodium falciparum exports
hundreds of proteins into the host erythrocyte. To enter the host cell, exported proteins must …

Throughout the latter half of this century, the development and spread of resistance to most
front-line antimalarial compounds used in the prevention and treatment of the most severe …

Several hundred malaria parasite proteins are exported beyond an encasing vacuole and
into the cytosol of the host erythrocyte, a process that is central to the virulence and viability …

Plasmodium parasites, the causative agents of malaria, have developed elaborate
strategies that they use to survive and thrive within different intracellular environments …

A major part of virulence for Plasmodium falciparum malaria infection, the most lethal
parasitic disease of humans, results from increased rigidity and adhesiveness of infected …