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[HTML][HTML] Futuristic food fortification with a balanced ratio of dietary ω-3/ω-6 omega fatty acids for the prevention of lifestyle diseases
Background Over the last three decades, consumption of total and saturated fat has steadily
declined in Western diets as a proportion of calories intake. At the same time, omega (ω)-6 …
declined in Western diets as a proportion of calories intake. At the same time, omega (ω)-6 …
[HTML][HTML] Expert opinion on benefits of long-chain omega-3 fatty acids (DHA and EPA) in aging and clinical nutrition
Life expectancy is increasing and so is the prevalence of age-related non-communicable
diseases (NCDs). Consequently, older people and patients present with multi-morbidities …
diseases (NCDs). Consequently, older people and patients present with multi-morbidities …
Protective effects of omega-3 fatty acids in cancer-related complications
Omega-3 polyunsaturated fatty acids (PUFAs) are considered immunonutrients and are
commonly used in the nutritional therapy of cancer patients due to their ample biological …
commonly used in the nutritional therapy of cancer patients due to their ample biological …
The influence of omega-3 fatty acids on skeletal muscle protein turnover in health, disuse, and disease
Ingestion of omega-3 fatty acids is known to exert favorable health effects on a number of
biological processes such as improved immune profile, enhanced cognition, and optimized …
biological processes such as improved immune profile, enhanced cognition, and optimized …
Current therapeutic targets in cancer cachexia: a pathophysiologic approach
Significant progress in our understanding of cancer cachexia has occurred in recent years.
Despite these advances, no pharmacologic agent has achieved US Food and Drug …
Despite these advances, no pharmacologic agent has achieved US Food and Drug …
High-dose eicosapentaenoic acid (EPA) improves attention and vigilance in children and adolescents with attention deficit hyperactivity disorder (ADHD) and low …
No studies have examined the relationship between endogenous polyunsaturated fatty
acids (PUFAs) levels and treatment response to PUFAs. We conducted a 12-week, double …
acids (PUFAs) levels and treatment response to PUFAs. We conducted a 12-week, double …
FADS2 function at the major cancer hotspot 11q13 locus alters fatty acid metabolism in cancer
Dysregulation of fatty acid metabolism and de novo lipogenesis is a key driver of several
cancer types through highly unsaturated fatty acid (HUFA) signaling precursors such as …
cancer types through highly unsaturated fatty acid (HUFA) signaling precursors such as …
Targeting mitochondria and oxidative stress in cancer-and chemotherapy-induced muscle wasting
Significance: Cancer is frequently associated with the early appearance of cachexia, a
multifactorial wasting syndrome. If not present at diagnosis, cachexia develops either as a …
multifactorial wasting syndrome. If not present at diagnosis, cachexia develops either as a …
High levels of modified ceramides are a defining feature of murine and human cancer cachexia
Abstract Background Cancer cachexia (CCx) is a multifactorial energy‐wasting syndrome
reducing the efficiency of anti‐cancer therapies, quality of life, and survival of cancer …
reducing the efficiency of anti‐cancer therapies, quality of life, and survival of cancer …
[HTML][HTML] Ketogenic diets in pancreatic cancer and associated cachexia: cellular mechanisms and clinical perspectives
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and extremely therapy-resistant
cancer. It is estimated that up to 80% of PDAC patients present with cachexia, a multifactorial …
cancer. It is estimated that up to 80% of PDAC patients present with cachexia, a multifactorial …