The kidneys have a central role in the control of acid–base homeostasis owing to
bicarbonate reabsorption and production of ammonia and ammonium in the proximal tubule …

The kidney plays a pivotal role in regulating calcium levels within the body. Approximately
98% of the filtered calcium is reabsorbed in the nephron, and this process is tightly …

Multiple disciplines are involved in the management of diabetic foot disease, and a common
vocabulary is essential for clear communication. Based on the systematic reviews of the …

Background Primary distal renal tubular acidosis (dRTA) is a rare disorder, and we aimed to
gather data on treatment and long-term outcome. Methods We contacted paediatric and …

Prevention of foot ulcers in patients with diabetes is important to help reduce the substantial
burden on both patient and health resources. A comprehensive analysis of reported …

Nephrolithiasis is a worldwide problem with increasing prevalence, enormous costs, and
significant morbidity. Calcium-containing kidney stones are by far the most common kidney …

Purpose Changes in dietary protein intake metabolically affect kidney functions. However,
knowledge on potential adverse consequences of long-term higher protein intake (HPI) for …

Distal renal tubular acidosis (dRTA) is characterized by an impaired ability of the distal
tubule to excrete acid, leading to metabolic acidosis. Associated complications include bone …

The identification of genes causing inherited kidney diseases yielded crucial insights in the
molecular basis of disease and improved our understanding of physiological processes that …

Kidney tubules are responsible for the preservation of fluid, electrolyte and acid-base
homeostasis via passive and active mechanisms. These physiological processes can be …