A meta-analysis investigating the relationship between inflammation in autoimmune disease, elevated CRP, and the risk of dementia
Alzheimer's Disease (AD) represents the most common type of dementia and is becoming a
steadily increasing challenge for health systems globally. Inflammation is develo** as the …
steadily increasing challenge for health systems globally. Inflammation is develo** as the …
C-reactive protein: the most familiar stranger
SR Ji, SH Zhang, Y Chang, HY Li, MY Wang… - The Journal of …, 2023 - journals.aai.org
C-reactive protein (CRP) is a highly conserved pentraxin with pattern recognition receptor–
like activities. However, despite being used widely as a clinical marker of inflammation, the …
like activities. However, despite being used widely as a clinical marker of inflammation, the …
Vascular injury is associated with repetitive head impacts and tau pathology in chronic traumatic encephalopathy
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease linked to repetitive
head impacts (RHI) and characterized by perivascular hyperphosphorylated tau (p-tau) …
head impacts (RHI) and characterized by perivascular hyperphosphorylated tau (p-tau) …
Monomeric C-reactive protein: current perspectives for utilization and inclusion as a prognostic indicator and therapeutic target
Monomeric C-reactive protein (mCRP), once thought to be a figment of the imagination and
whose biological activity was ascribed to its sodium azide preservative, has now …
whose biological activity was ascribed to its sodium azide preservative, has now …
Monomeric C‐reactive protein: a novel biomarker predicting neurodegenerative disease and vascular dysfunction
Circulating C‐reactive protein (pCRP) concentrations rise dramatically during both acute
(eg, following stroke) or chronic infection and disease (eg, autoimmune conditions such as …
(eg, following stroke) or chronic infection and disease (eg, autoimmune conditions such as …
Transcranial Electromagnetic Treatment Stops Alzheimer's Disease Cognitive Decline over a 2½-Year Period: A Pilot Study
G Arendash, H Abulaban, S Steen, R Andel, Y Wang… - Medicines, 2022 - mdpi.com
Background: There is currently no therapeutic that can stop or reverse the progressive
memory impairment of Alzheimer's disease (AD). However, we recently published that 2 …
memory impairment of Alzheimer's disease (AD). However, we recently published that 2 …
Evidence of genetic overlap and causal relationships between blood-based biochemical traits and human cortical anatomy
Psychiatric disorders such as schizophrenia are commonly associated with structural brain
alterations affecting the cortex. Recent genetic evidence suggests circulating metabolites …
alterations affecting the cortex. Recent genetic evidence suggests circulating metabolites …
Monomeric C-reactive protein as a biomarker for major depressive disorder
MG Hornick, LA Potempa - Frontiers in Psychiatry, 2024 - frontiersin.org
Neuroinflammation has been postulated to be a key factor in the pathogenesis of major
depressive disorder (MDD). With this is mind, there has been a wave of research looking …
depressive disorder (MDD). With this is mind, there has been a wave of research looking …
Pentameric C-reactive protein is a better prognostic biomarker and remains elevated for longer than monomeric CRP in hospitalized patients with COVID-19
The differing roles of the pentameric (p) and monomeric (m) C-reactive protein (CRP)
isoforms in viral diseases are not fully understood, which was apparent during the COVID-19 …
isoforms in viral diseases are not fully understood, which was apparent during the COVID-19 …
Structurally altered, not wild-type, pentameric C-reactive protein inhibits formation of amyloid-β fibrils
DN Ngwa, A Agrawal - The Journal of Immunology, 2022 - journals.aai.org
The structure of wild-type pentameric C-reactive protein (CRP) is stabilized by two calcium
ions that are required for the binding of CRP to its ligand phosphocholine. CRP in its …
ions that are required for the binding of CRP to its ligand phosphocholine. CRP in its …