In an effort to reveal susceptibility genes, schizophrenia research has turned to the
endophenotype strategy. Endophenotypes are characteristics that reflect the actions of …

Introduction: Electrophysiological (EEG) abnormalities in subjects with schizophrenia have
been largely reported. In the last decades, research has shifted to the identification of …

The genetics of schizophrenia has been approached utilizing a variety of methods. One
emerging strategy is the use of endophenotypes in order to understand and identify the …

Context Exploration of the genetic architecture of specific endophenotypes may be a
powerful strategy for understanding the genetic basis of schizophrenia. Objective To …

Tobacco dependence among individuals with a mental illness or an addiction is a
tremendous problem that goes largely ignored. Studies of genetics, neuroimaging, and …

Schizophrenia represents a pervasive deficit in brain function, leading to hallucinations and
delusions, social withdrawal and a decline in cognitive performance. As the underlying …

Many studies have found that the P50 sensory gating ratio in a paired click task is smaller in
normal control subjects than in patients with schizophrenia, indicating more effective …

Generalized cognitive impairments are stable deficits linked to schizophrenia and key
factors associated with functional disability in the disorder. Preclinical data suggest that …

Rationale and objective Auditory sensory gating, a biological measurement of the ability to
suppress the evoked response to the second of two auditory stimuli, is diminished in people …

Marijuana is the world's most popular illicit drug, with hundreds of millions of regular users
worldwide. One in three Americans has smoked pot at least once. The Drug Enforcement …