Artificial intelligence to deep learning: machine intelligence approach for drug discovery

R Gupta, D Srivastava, M Sahu, S Tiwari, RK Ambasta… - Molecular …, 2021 - Springer
Drug designing and development is an important area of research for pharmaceutical
companies and chemical scientists. However, low efficacy, off-target delivery, time …

Deep learning for drug repurposing: Methods, databases, and applications

X Pan, X Lin, D Cao, X Zeng, PS Yu… - Wiley …, 2022 - Wiley Online Library
Drug development is time‐consuming and expensive. Repurposing existing drugs for new
therapies is an attractive solution that accelerates drug development at reduced …

[HTML][HTML] Advances in Artificial Intelligence (AI)-assisted approaches in drug screening

S Singh, H Gupta, P Sharma, S Sahi - Artificial Intelligence Chemistry, 2024 - Elsevier
Artificial intelligence (AI) is revolutionizing the current process of drug design and
development, addressing the challenges encountered in its various stages. By utilizing AI …

A revolution of personalized healthcare: Enabling human digital twin with mobile AIGC

J Chen, C Yi, H Du, D Niyato, J Kang, J Cai… - IEEE …, 2024 - ieeexplore.ieee.org
Mobile artificial intelligence-generated content (AIGC) refers to the adoption of generative
artificial intelligence (GAI) algorithms deployed at mobile edge networks to automate the …

Artificial intelligence-driven biomedical genomics

K Guo, M Wu, Z Soo, Y Yang, Y Zhang, Q Zhang… - Knowledge-Based …, 2023 - Elsevier
As genomic research becomes more complex and data-rich, artificial intelligence (AI) has
emerged as a crucial tool for processing and analyzing high-dimensional genomic data …

Generative AI-driven human digital twin in IoT-healthcare: A comprehensive survey

J Chen, Y Shi, C Yi, H Du, J Kang… - IEEE Internet of Things …, 2024 - ieeexplore.ieee.org
The Internet of Things (IoT) can significantly enhance the quality of human life, specifically in
healthcare, attracting extensive attentions to IoT healthcare services. Meanwhile, the human …

siVAE: interpretable deep generative models for single-cell transcriptomes

Y Choi, R Li, G Quon - Genome Biology, 2023 - Springer
Neural networks such as variational autoencoders (VAE) perform dimensionality reduction
for the visualization and analysis of genomic data, but are limited in their interpretability: it is …

Low rank matrix factorization algorithm based on multi-graph regularization for detecting drug-disease association

C Ai, H Yang, Y Ding, J Tang… - IEEE/ACM Transactions …, 2023 - ieeexplore.ieee.org
Detecting potential associations between drugs and diseases plays an indispensable role in
drug development, which has also become a research hotspot in recent years. Compared …

AMDGT: Attention aware multi-modal fusion using a dual graph transformer for drug–disease associations prediction

J Liu, S Guan, Q Zou, H Wu, P Tiwari, Y Ding - Knowledge-Based Systems, 2024 - Elsevier
Identification of new indications for existing drugs is crucial through the various stages of
drug discovery. Computational methods are valuable in establishing meaningful …

Associative learning mechanism for drug‐target interaction prediction

Z Zhu, Z Yao, G Qi, N Mazur, P Yang… - CAAI Transactions on …, 2023 - Wiley Online Library
As a necessary process of modern drug development, finding a drug compound that can
selectively bind to a specific protein is highly challenging and costly. Exploring drug‐target …