Pyrazolone structural motif in medicinal chemistry: Retrospect and prospect
Z Zhao, X Dai, C Li, X Wang, J Tian, Y Feng… - European journal of …, 2020 - Elsevier
The pyrazolone structural motif is a critical element of drugs aimed at different biological end-
points. Medicinal chemistry researches have synthesized drug-like pyrazolone candidates …
points. Medicinal chemistry researches have synthesized drug-like pyrazolone candidates …
Visible light photocatalysis in the synthesis of pharmaceutically relevant heterocyclic scaffolds
Visible light and photoredox catalysis have emerged as a powerful and long-lasting tool for
organic synthesis, demonstrating the importance of a variety of chemical bond formation …
organic synthesis, demonstrating the importance of a variety of chemical bond formation …
Pharmacological aspects of schiff base metal complexes: A critical review
T Ashraf, B Ali, H Qayyum, MS Haroone… - Inorganic Chemistry …, 2023 - Elsevier
Multidrug-resistant infections have placed a financial and health burden on the health-care
system and population. As a result, human health was faced major issues due to multidrug …
system and population. As a result, human health was faced major issues due to multidrug …
Antibacterial and antioxidant activities for natural and synthetic dual-active compounds
G Martelli, D Giacomini - European Journal of Medicinal Chemistry, 2018 - Elsevier
Antimicrobial resistance is widely recognized as a grave threat to global health in the 21st
century, since the past decades have seen a dramatic increase in human-pathogenic …
century, since the past decades have seen a dramatic increase in human-pathogenic …
Catalyst-free organic transformations under visible-light
Pollutants from industry and chemical laboratories have harmful effects on human health
and the environment. Concerns about this problem have led to the development of more …
and the environment. Concerns about this problem have led to the development of more …
Synthesis, anti-bacterial and anti-fungal activities of some novel Schiff bases containing 2, 4-disubstituted thiazole ring
A series of arylidene-2-(4-(4-methoxy/bromophenyl) thiazol-2-yl) hydrazines (4a–z) and 1-(4-
(4-methoxy/bromophenyl) thiazol-2-yl)-2-cyclohexylidene/cyclopentylidene hydrazines (5a …
(4-methoxy/bromophenyl) thiazol-2-yl)-2-cyclohexylidene/cyclopentylidene hydrazines (5a …
Thiazoles: having diverse biological activities
In the last few decades, a lot of work has been done on thiazole ring to find new compounds
related to this scaffold to act as antioxidant, analgesic, anti-inflammatory, antimicrobial …
related to this scaffold to act as antioxidant, analgesic, anti-inflammatory, antimicrobial …
[PDF][PDF] Thiazoles: a valuable insight into the recent advances and biological activities
Thiazoles displayed broad range of biological activities and found in many potent
biologically active molecules such as Sulfathiazol (antimicrobial drug), Ritonavir …
biologically active molecules such as Sulfathiazol (antimicrobial drug), Ritonavir …
Synthesis, characterization, and pharmacological evaluation of some novel thiadiazoles and thiazoles incorporating pyrazole moiety as anticancer agents
Abstract Two series of novel 2-[[1-(5-methyl-1-phenyl-5-substituted-1 H-pyrazol-4-yl)
ethylidene] hydrazono]-3-phenyl-2, 3-dihydro-1, 3, 4-thiadiazole derivatives and 2-[5-(4 …
ethylidene] hydrazono]-3-phenyl-2, 3-dihydro-1, 3, 4-thiadiazole derivatives and 2-[5-(4 …
Design and synthesis of some thiazolyl and thiadiazolyl derivatives of antipyrine as potential non-acidic anti-inflammatory, analgesic and antimicrobial agents
The synthesis of two groups of structure hybrids comprising basically the antipyrine moiety
attached to either polysubstituted thiazole or 2, 5-disubstituted-1, 3, 4-thiadiazole …
attached to either polysubstituted thiazole or 2, 5-disubstituted-1, 3, 4-thiadiazole …