Lipid-based DNA therapeutics: hallmarks of non-viral gene delivery
Gene therapy is a promising strategy for the treatment of monogenic disorders. Non-viral
gene delivery systems including lipid-based DNA therapeutics offer the opportunity to …
gene delivery systems including lipid-based DNA therapeutics offer the opportunity to …
[HTML][HTML] The past, present, and future of breast cancer models for nanomedicine development
P Boix-Montesinos, PM Soriano-Teruel… - Advanced drug delivery …, 2021 - Elsevier
Even given recent advances in nanomedicine development of breast cancer treatment in
recent years and promising results in pre-clinical models, cancer nanomedicines often fail at …
recent years and promising results in pre-clinical models, cancer nanomedicines often fail at …
Anionic lipid nanoparticles preferentially deliver mRNA to the hepatic reticuloendothelial system
Lipid nanoparticles (LNPs) are the leading nonviral technologies for the delivery of
exogenous RNA to target cells in vivo. As systemic delivery platforms, these technologies …
exogenous RNA to target cells in vivo. As systemic delivery platforms, these technologies …
Are nano-pesticides really meant for cleaner production? An overview on recent developments, benefits, environmental hazards and future prospectives
The world is seeking hard for sustainable agricultural practices with one of the prime
objectives to improve crop yield through effective pest management. Scientific diaspora has …
objectives to improve crop yield through effective pest management. Scientific diaspora has …
Cardiovascular toxicity assessment of polyethylene nanoplastics on develo** zebrafish embryos
M Sun, R Ding, Y Ma, Q Sun, X Ren, Z Sun, J Duan - Chemosphere, 2021 - Elsevier
Environmental exposure to nanoplastics is inevitable as the application of nanoplastics in
our daily life is more and more extensively. So, the adverse effects of nanoplastics on human …
our daily life is more and more extensively. So, the adverse effects of nanoplastics on human …
Current hurdles to the translation of nanomedicines from bench to the clinic
The field of nanomedicine has significantly influenced research areas such as drug delivery,
diagnostics, theranostics, and regenerative medicine; however, the further development of …
diagnostics, theranostics, and regenerative medicine; however, the further development of …
Nanomaterials meet zebrafish: Toxicity evaluation and drug delivery applications
With the rapid development of engineered nanomaterials for various applications, in vivo
toxicological studies for evaluating the potential hazardous effects of nanomaterials on …
toxicological studies for evaluating the potential hazardous effects of nanomaterials on …
Light-triggered switching of liposome surface charge directs delivery of membrane impermeable payloads in vivo
G Arias-Alpizar, L Kong, RC Vlieg, A Rabe… - Nature …, 2020 - nature.com
Surface charge plays a fundamental role in determining the fate of a nanoparticle, and any
encapsulated contents, in vivo. Herein, we describe, and visualise in real time, light …
encapsulated contents, in vivo. Herein, we describe, and visualise in real time, light …
Metal–organic framework assisted and tumor microenvironment modulated synergistic image‐guided photo‐chemo therapy
The complex tumor microenvironment (TME) and nonspecific drug targeting limit the clinical
efficacy of photodynamic therapy in combination with chemotherapy. Herein, a metal …
efficacy of photodynamic therapy in combination with chemotherapy. Herein, a metal …
[HTML][HTML] Advanced optical imaging for the rational design of nanomedicines
Despite the enormous potential of nanomedicines to shape the future of medicine, their
clinical translation remains suboptimal. Translational challenges are present in every step of …
clinical translation remains suboptimal. Translational challenges are present in every step of …