Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus.
The loss of T helper cell (TH) function in asymptomatic HIV type 1-infected individuals occurs
before the decline in CD4+ T cells. At least part of the loss in TH function results from …
before the decline in CD4+ T cells. At least part of the loss in TH function results from …
Cell-mediated immune response to human immunodeficiency virus (HIV) type 1 in seronegative homosexual men with recent sexual exposure to HIV-1
M Clerici, JV Giorgi, CC Chou… - Journal of Infectious …, 1992 - academic.oup.com
Although human immunodeficiency virus (HIV) type 1 infection is efficiently transmitted by
sexual intercourse, some individuals whose sexual behavior places them at extremely high …
sexual intercourse, some individuals whose sexual behavior places them at extremely high …
Human immunodeficiency virus (HIV)–specific cellular immune responses in newborns exposed to HIV in utero
Significant immunological changes are associated with intrauterine human
immunodeficiency virus (HIV) encounter among uninfected infants of HIV-infected mothers …
immunodeficiency virus (HIV) encounter among uninfected infants of HIV-infected mothers …
Approaches to improve engineered vaccines for human immunodeficiency virus and other viruses that cause chronic infections
JA Berzofsky, JD Ahlers, MA Derby… - Immunological …, 1999 - Wiley Online Library
We used several approaches to develop enhanced vaccines for chronic viral infections such
as human immunodeficiency virus (HIV) and hepatitis C virus (HCV), I) Selected epitopes …
as human immunodeficiency virus (HIV) and hepatitis C virus (HCV), I) Selected epitopes …
Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro
Peripheral blood mononuclear cells (PBMCs) from many asymptomatic individuals infected
with human immunodeficiency virus-type 1 (HIV) are unresponsive as measured by in vitro T …
with human immunodeficiency virus-type 1 (HIV) are unresponsive as measured by in vitro T …
ENV-specific cytotoxic T lymphocyte responses in HIV seronegative health care workers occupationally exposed to HIV-contaminated body fluids.
Identification of the components of protective immunity are crucial for the development of
effective prophylactic and therapeutic vaccine strategies. Analysis of HIV-specific responses …
effective prophylactic and therapeutic vaccine strategies. Analysis of HIV-specific responses …
HIV-specific T-helper activity in seronegative health care workers exposed to contaminated blood
Objective.—To evaluate human immunodeficiency virus (HIV) type 1—specific cellular
immune responses in HIV-seronegative health care workers with occupational high-risk …
immune responses in HIV-seronegative health care workers with occupational high-risk …
Identification and antigenicity of broadly cross-reactive and conserved human immunodeficiency virus type 1-derived helper T-lymphocyte epitopes
Human immunodeficiency virus (HIV)-specific helper T lymphocytes (HTL) play a key role in
the immune control of HIV type 1 (HIV-1) infection, and as such are an important target of …
the immune control of HIV type 1 (HIV-1) infection, and as such are an important target of …
Localization of CD4+ T cell epitope hotspots to exposed strands of HIV envelope glycoprotein suggests structural influences on antigen processing
S Surman, TD Lockey, KS Slobod… - Proceedings of the …, 2001 - National Acad Sciences
The spectrum of immunogenic epitopes presented by the H2-IAb MHC class II molecule to
CD4+ T cells has been defined for two different (clade B and clade D) HIV envelope (gp140) …
CD4+ T cells has been defined for two different (clade B and clade D) HIV envelope (gp140) …
Induction of cross-reactive cytotoxic T-lymphocyte responses specific for HIV-1 gp120 using saponin adjuvant (QS-21) supplemented subunit vaccine formulations
MJ Newman, JY Wu, BH Gardner, CA Anderson… - Vaccine, 1997 - Elsevier
The antigenic variation associated with Human Immunodeficiency Virus type-1 (HIV-1)
envelope proteins could limit their utility in vaccines if the immune responses induced are …
envelope proteins could limit their utility in vaccines if the immune responses induced are …