Nanochitin: chemistry, structure, assembly, and applications
Chitin, a fascinating biopolymer found in living organisms, fulfills current demands of
availability, sustainability, biocompatibility, biodegradability, functionality, and renewability …
availability, sustainability, biocompatibility, biodegradability, functionality, and renewability …
Nitrogen-Centered Radicals in Functionalization of sp2 Systems: Generation, Reactivity, and Applications in Synthesis
C Pratley, S Fenner, JA Murphy - Chemical reviews, 2022 - ACS Publications
The chemistry of nitrogen-centered radicals (NCRs) has plentiful applications in organic
synthesis, and they continue to expand as our understanding of these reactive species …
synthesis, and they continue to expand as our understanding of these reactive species …
Analysis of past and present synthetic methodologies on medicinal chemistry: where have all the new reactions gone? Miniperspective
An analysis of chemical reactions used in current medicinal chemistry (2014), three decades
ago (1984), and in natural product total synthesis has been conducted. The analysis …
ago (1984), and in natural product total synthesis has been conducted. The analysis …
Exploiting the Marcus inverted region for first-row transition metal–based photoredox catalysis
Second-and third-row transition metal complexes are widely employed in photocatalysis,
whereas earth-abundant first-row transition metals have found only limited use because of …
whereas earth-abundant first-row transition metals have found only limited use because of …
Mechanism of CN bonds formation in electrocatalytic urea production revealed by ab initio molecular dynamics simulation
Electrosynthesis of urea from CO2 and NOX provides an exceptional opportunity for human
society, given the increasingly available renewable energy. Urea electrosynthesis is …
society, given the increasingly available renewable energy. Urea electrosynthesis is …
Applications of acceptorless dehydrogenation and related transformations in chemical synthesis
Background Acceptorless dehydrogenation (AD) reactions can result not only in simple
removal of hydrogen gas from various substrates but also, importantly, in surprisingly …
removal of hydrogen gas from various substrates but also, importantly, in surprisingly …
Nonclassical routes for amide bond formation
RM De Figueiredo, JS Suppo, JM Campagne - Chemical reviews, 2016 - ACS Publications
The present review offers an overview of nonclassical (eg, with no pre-or in situ activation of
a carboxylic acid partner) approaches for the construction of amide bonds. The review aims …
a carboxylic acid partner) approaches for the construction of amide bonds. The review aims …
Native chemical ligation and extended methods: mechanisms, catalysis, scope, and limitations
V Agouridas, O El Mahdi, V Diemer, M Cargoet… - Chemical …, 2019 - ACS Publications
The native chemical ligation reaction (NCL) involves reacting a C-terminal peptide thioester
with an N-terminal cysteinyl peptide to produce a native peptide bond between the two …
with an N-terminal cysteinyl peptide to produce a native peptide bond between the two …
Key Green Chemistry research areas from a pharmaceutical manufacturers' perspective revisited
MC Bryan, PJ Dunn, D Entwistle, F Gallou… - Green …, 2018 - pubs.rsc.org
In 2007 the members of the ACS Green Chemistry Institute® Pharmaceutical Roundtable
assembled a list of key green chemistry research areas to both identify transformations that …
assembled a list of key green chemistry research areas to both identify transformations that …
Amide bond bioisosteres: Strategies, synthesis, and successes
The amide functional group plays a key role in the composition of biomolecules, including
many clinically approved drugs. Bioisosterism is widely employed in the rational …
many clinically approved drugs. Bioisosterism is widely employed in the rational …