Microglia, as immune cells in the central nervous system, are closely related to cognitive
impairment associated with type 2 diabetes (T2D). Preliminary explorations have …

Medin amyloid, prevalent in the vessel walls of 97% of individuals over 50, contributes to
arterial stiffening and cerebrovascular dysfunction, yet our understanding of its aggregation …

In classical amyloidoses, amyloid fibres form through the nucleation and accretion of protein
monomers, with protofibrils and fibrils exhibiting a cross-β motif of parallel or antiparallel β …

Amyloids are protein fibrils with a characteristic cross-β structure that is responsible for the
unusual resistance of amyloids to various physical and chemical factors, as well as …

Emerging evidence suggests that physiological C-terminal truncation of α-synuclein (αS)
plays a critical role in regulating liquid–liquid phase separation and promoting amyloid …

Pathological aggregation of essentially dissociated Transthyretin (TTR) monomer proteins,
driven by misfolding and self-interaction, is associated with Transthyretin amyloidosis …

The formation of functional bacterial amyloids by phenol-soluble modulins (PSMs) in
Staphylococcus aureus is a critical component of biofilm-associated infections, providing …