Radiomics: the bridge between medical imaging and personalized medicine

P Lambin, RTH Leijenaar, TM Deist… - Nature reviews Clinical …, 2017 - nature.com
Radiomics, the high-throughput mining of quantitative image features from standard-of-care
medical imaging that enables data to be extracted and applied within clinical-decision …

The 2019 mathematical oncology roadmap

RC Rockne, A Hawkins-Daarud, KR Swanson… - Physical …, 2019 - iopscience.iop.org
Whether the nom de guerre is Mathematical Oncology, Computational or Systems Biology,
Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is …

Mathematical models of cancer: when to predict novel therapies, and when not to

R Brady, H Enderling - Bulletin of mathematical biology, 2019 - Springer
The number of publications on mathematical modeling of cancer is growing at an
exponential rate, according to PubMed records, provided by the US National Library of …

The future of personalised radiotherapy for head and neck cancer

JJ Caudell, JF Torres-Roca, RJ Gillies… - The Lancet …, 2017 - thelancet.com
Radiotherapy has long been the mainstay of treatment for patients with head and neck
cancer and has traditionally involved a stage-dependent strategy whereby all patients with …

Turnover modulates the need for a cost of resistance in adaptive therapy

MAR Strobl, J West, Y Viossat, M Damaghi… - Cancer research, 2021 - AACR
Adaptive therapy seeks to exploit intratumoral competition to avoid, or at least delay, the
emergence of therapy resistance in cancer. Motivated by promising results in prostate …

Differences in predictions of ODE models of tumor growth: a cautionary example

H Murphy, H Jaafari, HM Dobrovolny - BMC cancer, 2016 - Springer
Background While mathematical models are often used to predict progression of cancer and
treatment outcomes, there is still uncertainty over how to best model tumor growth. Seven …

Improving cancer treatments via dynamical biophysical models

M Kuznetsov, J Clairambault, V Volpert - Physics of life reviews, 2021 - Elsevier
Despite significant advances in oncological research, cancer nowadays remains one of the
main causes of mortality and morbidity worldwide. New treatment techniques, as a rule …

Mathematical models of tumor cell proliferation: A review of the literature

AM Jarrett, EABF Lima, DA Hormuth… - Expert review of …, 2018 - Taylor & Francis
Introduction: A defining hallmark of cancer is aberrant cell proliferation. Efforts to understand
the generative properties of cancer cells span all biological scales: from genetic deviations …

Image-based personalization of computational models for predicting response of high-grade glioma to chemoradiation

DA Hormuth, KA Al Feghali, AM Elliott, TE Yankeelov… - Scientific reports, 2021 - nature.com
High-grade gliomas are an aggressive and invasive malignancy which are susceptible to
treatment resistance due to heterogeneity in intratumoral properties such as cell proliferation …

Spatial structure impacts adaptive therapy by sha** intra-tumoral competition

MAR Strobl, J Gallaher, J West… - Communications …, 2022 - nature.com
Background Adaptive therapy aims to tackle cancer drug resistance by leveraging resource
competition between drug-sensitive and resistant cells. Here, we present a theoretical study …