Radiomics: the bridge between medical imaging and personalized medicine
Radiomics, the high-throughput mining of quantitative image features from standard-of-care
medical imaging that enables data to be extracted and applied within clinical-decision …
medical imaging that enables data to be extracted and applied within clinical-decision …
The 2019 mathematical oncology roadmap
Whether the nom de guerre is Mathematical Oncology, Computational or Systems Biology,
Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is …
Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is …
Mathematical models of cancer: when to predict novel therapies, and when not to
The number of publications on mathematical modeling of cancer is growing at an
exponential rate, according to PubMed records, provided by the US National Library of …
exponential rate, according to PubMed records, provided by the US National Library of …
The future of personalised radiotherapy for head and neck cancer
Radiotherapy has long been the mainstay of treatment for patients with head and neck
cancer and has traditionally involved a stage-dependent strategy whereby all patients with …
cancer and has traditionally involved a stage-dependent strategy whereby all patients with …
Turnover modulates the need for a cost of resistance in adaptive therapy
Adaptive therapy seeks to exploit intratumoral competition to avoid, or at least delay, the
emergence of therapy resistance in cancer. Motivated by promising results in prostate …
emergence of therapy resistance in cancer. Motivated by promising results in prostate …
Differences in predictions of ODE models of tumor growth: a cautionary example
Background While mathematical models are often used to predict progression of cancer and
treatment outcomes, there is still uncertainty over how to best model tumor growth. Seven …
treatment outcomes, there is still uncertainty over how to best model tumor growth. Seven …
Improving cancer treatments via dynamical biophysical models
Despite significant advances in oncological research, cancer nowadays remains one of the
main causes of mortality and morbidity worldwide. New treatment techniques, as a rule …
main causes of mortality and morbidity worldwide. New treatment techniques, as a rule …
Mathematical models of tumor cell proliferation: A review of the literature
Introduction: A defining hallmark of cancer is aberrant cell proliferation. Efforts to understand
the generative properties of cancer cells span all biological scales: from genetic deviations …
the generative properties of cancer cells span all biological scales: from genetic deviations …
Image-based personalization of computational models for predicting response of high-grade glioma to chemoradiation
High-grade gliomas are an aggressive and invasive malignancy which are susceptible to
treatment resistance due to heterogeneity in intratumoral properties such as cell proliferation …
treatment resistance due to heterogeneity in intratumoral properties such as cell proliferation …
Spatial structure impacts adaptive therapy by sha** intra-tumoral competition
Background Adaptive therapy aims to tackle cancer drug resistance by leveraging resource
competition between drug-sensitive and resistant cells. Here, we present a theoretical study …
competition between drug-sensitive and resistant cells. Here, we present a theoretical study …