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Defending against SARS-CoV-2: The T cell perspective
P Almendro-Vázquez, R Laguna-Goya… - Frontiers in …, 2023 - frontiersin.org
SARS-CoV-2-specific T cell response has been proven essential for viral clearance, COVID-
19 outcome and long-term memory. Impaired early T cell-driven immunity leads to a severe …
19 outcome and long-term memory. Impaired early T cell-driven immunity leads to a severe …
Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA. 5 Omicron variant in mice
SM Scheaffer, D Lee, B Whitener, B Ying, K Wu… - Nature medicine, 2023 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
in the Omicron lineage has resulted in diminished Coronavirus Disease 2019 (COVID-19) …
in the Omicron lineage has resulted in diminished Coronavirus Disease 2019 (COVID-19) …
Predicting the efficacy of variant-modified COVID-19 vaccine boosters
Booster vaccination for the prevention of Coronavirus Disease 2019 (COVID-19) is required
to overcome loss of protection due to waning immunity and the spread of novel severe acute …
to overcome loss of protection due to waning immunity and the spread of novel severe acute …
Comparison of bivalent and monovalent SARS-CoV-2 variant vaccines: the phase 2 randomized open-label COVAIL trial
Vaccine protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection wanes over time, requiring updated boosters. In a phase 2, open-label, randomized …
infection wanes over time, requiring updated boosters. In a phase 2, open-label, randomized …
Map** SARS-CoV-2 antigenic relationships and serological responses
During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic,
multiple variants esca** preexisting immunity emerged, causing reinfections of previously …
multiple variants esca** preexisting immunity emerged, causing reinfections of previously …
BA. 2 and BA. 5 omicron differ immunologically from both BA. 1 omicron and pre-omicron variants
Several studies have shown that SARS-CoV-2 BA. 1 omicron is an immune escape variant.
Meanwhile, however, omicron BA. 2 and BA. 5 became dominant in many countries and …
Meanwhile, however, omicron BA. 2 and BA. 5 became dominant in many countries and …
[HTML][HTML] Post-vaccination neutralization responses to Omicron sub-variants
Background: The emergence of the Omicron variant (B. 1.1. 529), which correlated with
dramatic losses in cross-neutralization capacity of post-vaccination sera, raised concerns …
dramatic losses in cross-neutralization capacity of post-vaccination sera, raised concerns …
Characterizing SARS-CoV-2 neutralization profiles after bivalent boosting using antigenic cartography
Since emergence of the initial SARS-CoV-2 BA. 1, BA. 2 and BA. 5 variants, Omicron has
diversified substantially. Antigenic characterization of these new variants is important to …
diversified substantially. Antigenic characterization of these new variants is important to …
SARS-CoV-2 omicron BA. 5 and XBB variants have increased neurotropic potential over BA. 1 in K18-hACE2 mice and human brain organoids
The reduced pathogenicity of the omicron BA. 1 sub-lineage compared to earlier variants is
well described, although whether such attenuation is retained for later variants like BA. 5 …
well described, although whether such attenuation is retained for later variants like BA. 5 …
Exposure to BA. 4/5 S protein drives neutralization of Omicron BA. 1, BA. 2, BA. 2.12. 1, and BA. 4/5 in vaccine-experienced humans and mice
A Muik, BG Lui, M Bacher, AK Wallisch, A Toker… - Science …, 2022 - science.org
The SARS-CoV-2 Omicron variant and its sublineages show pronounced viral escape from
neutralizing antibodies elicited by vaccination or prior SARS-CoV-2 variant infection owing …
neutralizing antibodies elicited by vaccination or prior SARS-CoV-2 variant infection owing …