Introduction: Foldamers are artificial self-organizing systems with various critical properties:
i) a stable and designable secondary structure; ii) a larger molecular surface as compared …

The term “privileged structure” refers to a single molecular substructure or scaffold that can
serve as a starting point for high‐affinity ligands for more than one receptor type. In this …

The important role that G-quadruplex DNA (G4 DNA) structures play in regulating biological
processes is becoming widely recognised. These structures have also been proposed to be …

We report here a solid phase synthesis methodology that allows the incorporation of α-
amino acids (X) into quinoline (Q) oligoamide foldamer sequences. Water-soluble hybrid …

The tolerance of ribosomal peptide translation for helical aromatic oligoamide foldamers
appended as initiators has been investigated. Small cationic foldamer side-chains were …

The development of large synthetic ligands could be useful to target the sizeable surface
areas involved in protein–protein interactions. Herein, we present long helical aromatic …

Several small‐molecule ligands specifically bind and stabilize G‐quadruplex (G4) nucleic
acid structures, which are considered to be promising therapeutic targets. G4s are …

The growth of crystals of aromatic compounds from water much depends on the nature of the
water solubilizing functions that they carry. Rationalizing crystallization from water, and …

Telomeres are specialized chromatin structures that protect chromosome ends from
dangerous processing events. In most tissues, telomeres shorten with each round of cell …

Abstract Lead ions (Pb2+) are destructive to the natural environment and public health, so
the efficient detection of Pb2+ is particularly important. Although the instrumental analysis …